Crk family of adaptor molecules consists of CrkI with one SH2 and one SH3 domains and CrkII and CrkL with one SH2 and two SH3 domains each. They bind to Tyr762 of the PDGF alpha-receptor and represent the only known SH2-domain containing molecule which binds with significantly higher affinity to the alpha-receptor than to the beta-receptor.
Westermark, B, Heldin, CH
Saito, Y, Saito, Y, Mori, S, Ekman, S, Hellman, U, Yokote, K, Heldin, CH, Rönnstrand, L
Ostman, A, Heldin, CH, Rönnstrand, L
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