Recruitment of CDK11p58 to the centrosomes

Stable Identifier
R-HSA-380455
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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General
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CDK11p58 is a kinase that is active during mitosis when it associates with centrosomes, and has a crucial role in centrosome maturation and bipolar spindle formation (Petretti et al., 2006). CDK11p58 facilitates microtubule nucleation and is required for the recruitment of Aurora and Plk1 to the centrosome (Petretti et al., 2006).

Literature References
PubMed ID Title Journal Year
16462731 The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation

Petretti, C, Savoian, M, Montembault, E, Glover, DM, Prigent, C, Giet, R

EMBO Rep 2006
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created