asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate

Stable Identifier
R-HSA-379996
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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NARS (cytosolic asparaginyl tRNA synthetase) catalyzes the reaction of asparagine, tRNA(Asn), and ATP to form Asn-tRNA(Asn), AMP, and pyrophosphate. The enzyme is a class I tRNA synthetase (Beaulande et al. 1998).

Literature References
PubMed ID Title Journal Year
9421509 Human cytosolic asparaginyl-tRNA synthetase: cDNA sequence, functional expression in Escherichia coli and characterization as human autoantigen

Beaulande, M, Tarbouriech, N, Hartlein, M

Nucleic Acids Res 1998
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
asparagine-tRNA ligase activity of NARS [cytosol]
Physical Entity
Activity
Authored
Reviewed
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