serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate

Stable Identifier
R-HSA-379992
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate
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SARS (cytosolic seryl tRNA synthetase) catalyzes the reaction of serine, tRNA(Ser), and ATP to form Ser-tRNA(Ser), AMP, and pyrophosphate. The enzyme, a class II tRNA synthetase, is a homodimer (Hartlein and Cusack 1995; Vincent et al. 1997).
Literature References
PubMed ID Title Journal Year
9431993 Genomic organization, cDNA sequence, bacterial expression, and purification of human seryl-tRNA synthase

Hartlein, M, Vincent, C, Tarbouriech, N

Eur J Biochem 1997
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Catalyst Activity

serine-tRNA ligase activity of SARS dimer [cytosol]

Physical Entity
SARS dimer [cytosol] (Homo sapiens)
Activity
serine-tRNA ligase activity (GO:0004828)
Authored
D'Eustachio, P  (2008-11-29)
Reviewed
Antonellis, A  (2008-12-02)
Created
D'Eustachio, P  (2008-11-07)
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