histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate

Stable Identifier
R-HSA-379844
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate
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HARS (cytosolic histidyl tRNA synthetase) catalyzes the reaction of histidine, tRNA(His), and ATP to form His-tRNA(His), AMP, and pyrophosphate (Lee et al. 2002).
Literature References
PubMed ID Title Journal Year
11829477 Interaction network of human aminoacyl-tRNA synthetases and subunits of elongation factor 1 complex

Lee, JS, Park, SG, Park, H, Seol, W, Lee, S, Kim, S

Biochem Biophys Res Commun 2002
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Catalyst Activity

histidine-tRNA ligase activity of HARS [cytosol]

Physical Entity
HARS [cytosol] (Homo sapiens)
Activity
histidine-tRNA ligase activity (GO:0004821)
Authored
D'Eustachio, P  (2008-11-29)
Reviewed
Antonellis, A  (2008-12-02)
Created
D'Eustachio, P  (2008-11-06)
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