Luteinizing hormone (LH, lutropin) is a hormone produced by the anterior pituitary gland. In females it can trigger ovulation whereas in males it stimulates testosterone production. Like other glycoproteins, lutropin is composed of a common alpha subunit bound to a unique beta subunit (Sairam MR and Li CH, 1975). The beta subunit is responsible for lutropin's interaction with the LH receptor. N-Linked oligosaccharides terminating with the sequence SO(4)-4-GalNAcbeta1,4-GlcNAcbeta1,2-Manalpha are present on the pituitary hormones LH, thyrotropin, and pro-opiomelanocortin. These sulfated structures are essential for their biologic function (Fares 2006).
Li, CH, Sairam, MR
Fares, F
© 2023 Reactome
