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NR4A2 [nucleoplasm]
Stable Identifier
R-HSA-376305
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
NR4A2_HUMAN, Nuclear receptor subfamily 4 group A member 2
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Nuclear Receptor transcription pathway (Homo sapiens)
Formation of NR-MED1 Coactivator Complex (Homo sapiens)
NR [nucleoplasm] (Homo sapiens)
NR4A2 [nucleoplasm] (Homo sapiens)
NR-MED1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NR [nucleoplasm] (Homo sapiens)
NR4A2 [nucleoplasm] (Homo sapiens)
Formation of NR-NCOR Corepressor Complex (Homo sapiens)
NR [nucleoplasm] (Homo sapiens)
NR4A2 [nucleoplasm] (Homo sapiens)
NR-NCOR CoRepressor Complex [nucleoplasm] (Homo sapiens)
NR [nucleoplasm] (Homo sapiens)
NR4A2 [nucleoplasm] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
SUMOylation (Homo sapiens)
SUMO E3 ligases SUMOylate target proteins (Homo sapiens)
SUMOylation of intracellular receptors (Homo sapiens)
PIAS4 SUMOylates NR4A2 with SUMO2,3 (Homo sapiens)
NR4A2 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P43354 NR4A2
Gene Names
NR4A2, NOT, NURR1, TINUR
Chain
chain:1-598
Reference Genes
BioGPS Gene:4929 NR4A2
COSMIC (genes):NR4A2 NR4A2
CTD Gene:4929 NR4A2
dbSNP Gene:4929 NR4A2
ENSEMBL:ENSG00000153234 NR4A2
HGNC:7981 NR4A2
KEGG Gene (Homo sapiens):4929 NR4A2
Monarch:4929 NR4A2
NCBI Gene:4929 NR4A2
OMIM:601828 NR4A2
UCSC:P43354 NR4A2
Reference Transcript
RefSeq:XM_005246622.3 NR4A2
RefSeq:XM_017004219.1 NR4A2
RefSeq:NM_006186.3 NR4A2
Other Identifiers
0006980059
10481
11725631_a_at
11725632_at
11747474_a_at
16903897
1OVL
204621_s_at
204622_x_at
216248_s_at
2582125
2582126
2582127
2582128
2582129
2582130
2582132
2582135
2582136
2582138
2582140
2582141
2582142
2582146
2582150
2582159
2582160
37623_at
4929
543
547_s_at
5Y41
8055952
A_23_P131208
A_33_P3299066
AAB33999
AAH09288
AAH66890
AAY24203
AB017586
AB019433
AC074099
ADZ17335
AK291456
ALQ33696
BAA75666
BAA77328
BAF84145
BC009288
BC066890
C9IYM5
C9J8W4
C9JWQ1
CAA53518
CAB010481
CCDS2201
CCDS86887
CH471058
E9PBQ4
EAX11454
EAX11455
ENSG00000153234
ENSP00000344479
ENSP00000386747
ENSP00000389986
ENST00000339562
ENST00000339562.8
ENST00000409572
ENST00000409572.5
ENST00000426264
ENST00000426264.5
EntrezGene:4929
EntrezGene:NR4A2
F1D8N6
F8W6I3
GE79306
GO:0000122
GO:0000902
GO:0000977
GO:0000978
GO:0000981
GO:0001228
GO:0001666
GO:0001764
GO:0001975
GO:0003674
GO:0003677
GO:0003700
GO:0003707
GO:0004879
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005667
GO:0005737
GO:0006351
GO:0006355
GO:0006367
GO:0006950
GO:0007165
GO:0007267
GO:0007399
GO:0008013
GO:0008134
GO:0008150
GO:0008219
GO:0008270
GO:0008344
GO:0009058
GO:0009791
GO:0010467
GO:0010468
GO:0016607
GO:0021700
GO:0021952
GO:0021953
GO:0021986
GO:0030154
GO:0030182
GO:0030522
GO:0031668
GO:0032991
GO:0034599
GO:0034641
GO:0035259
GO:0040011
GO:0042053
GO:0042416
GO:0042417
GO:0042551
GO:0042803
GO:0043085
GO:0043167
GO:0043226
GO:0043401
GO:0043524
GO:0043565
GO:0043576
GO:0045444
GO:0045893
GO:0045944
GO:0046872
GO:0046965
GO:0046982
GO:0048856
GO:0048870
GO:0051866
GO:0060070
GO:0071376
GO:0071542
GO:1904948
GO:2001234
HGNC:7981
HPA000543
HQ692824
Hs.82120.0.S1_3p_a_at
Hs.82120.1.S1_3p_a_at
ILMN_1782305
ILMN_2339955
IPR000536
IPR001628
IPR001723
IPR003070
IPR003073
IPR013088
IPR035500
KU178238
MIM:168600
MIM:601828
NM_006186
NM_173173
NP_006177
NP_775265
NR4A2
NR4A2-201
NR4A2-204
NR4A2-209
PF00104
PF00105
PH_hs_0004696
PR00047
PR00398
PR01284
PR01287
S77154
S77154_s_at
SM00399
SM00430
TC02002445.hg
UPI0000036A18
UPI0000160FD7
X75918
X75918_at
XM_005246621
XM_006712553
XM_017004219
XM_017004220
XP_005246678
XP_006712616
XP_016859708
XP_016859709
XR_001738751
XR_001738752
XR_427087
Participant Of
input
PIAS4 SUMOylates NR4A2 with SUMO2,3
hasMember
NR [nucleoplasm]
Other forms of this molecule
SUMO2,3-K558,K577-NR4A2 [nucleoplasm]
Inferred To
NR4A1 [nucleoplasm] (Caenorhabditis elegans)
NR4A1 [nucleoplasm] (Drosophila melanogaster)
Nr4a2 [nucleoplasm] (Mus musculus)
NR4A2 [nucleoplasm] (Bos taurus)
NR4A2 [nucleoplasm] (Canis familiaris)
NR4A2 [nucleoplasm] (Danio rerio)
NR4A2 [nucleoplasm] (Gallus gallus)
NR4A2 [nucleoplasm] (Rattus norvegicus)
NR4A2 [nucleoplasm] (Sus scrofa)
NR4A2 [nucleoplasm] (Xenopus tropicalis)
Cross References
RefSeq
XP_005246679.1
,
NP_006177.1
,
XP_016859708.1
OpenTargets
ENSG00000153234
ZINC - Substances
NR4A2_HUMAN
GeneCards
P43354
ZINC target
P43354
PRO
P43354
ZINC - Predictions - Purchasable
NR4A2_HUMAN
PDB
6DDA
,
1OVL
,
5Y41
,
5YD6
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q5H9L2 TCAL5
0.524
2
UniProt:Q5T2S8 ARMC4
0.488
2
UniProt:P55273 CDKN2D
1
CDKN2D [cytosol]
(R-HSA-182580)
0.488
2
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