CCR7 (Epstein-Barr virus-induced gene 1, EBI1) (Birkenbach M, 1993; Schweickart VL et al, 1994) plays an important role in the trafficking of B and T lymphocytes and dendritic cells across high endothelial venules. Both CCL19 (Macrophage inflammatory protein 3 beta, MIP-3-beta; EBI1-ligand chemokine, ELC) (Yoshida R et al, 1997) and CCL21 (Secondary lymphoid-tissue chemokine, SLC; Beta chemokine exodus-2) (Yoshida R et al, 1998) bind specifically to CCR7.
Kieff, E, Yalamanchili, R, Josefsen, K, Birkenbach, M, Lenoir, G
Gray, PW, Byers, MG, Schweickart, VL, Shows, TB, Godiska, R, Raport, CJ
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