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CCR7 [plasma membrane]
Stable Identifier
R-HSA-373125
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
C-C chemokine receptor type 7, CCR7_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CCR7:CCL19,21 [plasma membrane] (Homo sapiens)
CCR7 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CCR7:CCL19,21 [plasma membrane] (Homo sapiens)
CCR7 [plasma membrane] (Homo sapiens)
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CCR7:CCL19,21 [plasma membrane] (Homo sapiens)
CCR7 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CCR7:CCL19,21 [plasma membrane] (Homo sapiens)
CCR7 [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CCR7:CCL19,21 [plasma membrane] (Homo sapiens)
CCR7 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CCR7:CCL19,21 [plasma membrane] (Homo sapiens)
CCR7 [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Peptide ligand-binding receptors (Homo sapiens)
Chemokine receptors bind chemokines (Homo sapiens)
Receptor CCR7 binds CCL19 and 21 ligands (Homo sapiens)
CCR7 [plasma membrane] (Homo sapiens)
CCR7:CCL19,21 [plasma membrane] (Homo sapiens)
CCR7 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P32248 CCR7
Gene Names
CCR7, CMKBR7, EBI1, EVI1
Chain
signal peptide:1-24, chain:25-378
Reference Genes
BioGPS Gene:1236 CCR7
COSMIC (genes):CCR7 CCR7
CTD Gene:1236 CCR7
dbSNP Gene:1236 CCR7
ENSEMBL:ENSG00000126353 CCR7
HGNC:1608 CCR7
KEGG:hsa:1236 CCR7
Monarch:1236 CCR7
NCBI Gene:1236 CCR7
OMIM:600242 CCR7
UCSC:P32248 CCR7
Reference Transcript
RefSeq:NM_001301714.1 CCR7
RefSeq:NM_001301716.1 CCR7
RefSeq:NM_001301717.1 CCR7
RefSeq:NM_001301718.1 CCR7
RefSeq:NM_001838.3 CCR7
Other Identifiers
1097_s_at
11725981_at
1236
16844381
206337_PM_at
206337_at
3756312
3756314
3756316
3756318
3756320
3756321
3756324
3756333
8015031
88629_at
A_23_P343398
GE667978
GE81076
GO:0001768
GO:0001954
GO:0002376
GO:0002407
GO:0002408
GO:0002606
GO:0002885
GO:0002922
GO:0004930
GO:0004950
GO:0005739
GO:0005886
GO:0006935
GO:0006954
GO:0006955
GO:0007163
GO:0007186
GO:0007204
GO:0009897
GO:0009986
GO:0016020
GO:0016493
GO:0019722
GO:0030154
GO:0030838
GO:0031274
GO:0031529
GO:0032496
GO:0032649
GO:0032651
GO:0032695
GO:0032735
GO:0034695
GO:0035757
GO:0035758
GO:0038115
GO:0038116
GO:0038117
GO:0038121
GO:0043123
GO:0043226
GO:0045060
GO:0045785
GO:0045860
GO:0046330
GO:0048870
GO:0048872
GO:0050862
GO:0051209
GO:0051491
GO:0051897
GO:0055085
GO:0060089
GO:0060326
GO:0070098
GO:0070374
GO:0071345
GO:0071731
GO:0090023
GO:0097022
GO:0097029
GO:2000147
GO:2000510
GO:2000522
GO:2000525
GO:2000526
GO:2000547
GO:2000669
HMNXSV003034420
ILMN_1715131
L31584_at
PH_hs_0000226
TC17001466.hg
g4502640_3p_at
Participates
as an input of
Receptor CCR7 binds CCL19 and 21 ligands (Homo sapiens)
as a component of
CCR7:CCL19,21 [plasma membrane] (Homo sapiens)
Inferred To
npr-32 [plasma membrane]
(Caenorhabditis elegans)
CCR7 [plasma membrane]
(Bos taurus)
CCR7 [plasma membrane]
(Canis familiaris)
CCR7 [plasma membrane]
(Gallus gallus)
CCR7 [plasma membrane]
(Sus scrofa)
ccr7 [plasma membrane]
(Danio rerio)
ccr7 [plasma membrane]
(Xenopus tropicalis)
Ccr7 [plasma membrane]
(Mus musculus)
Ccr7 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_001829.1
,
NP_001288643.1
,
NP_001288647.1
,
NP_001288645.1
,
NP_001288646.1
Guide to Pharmacology - Targets
64
ENSEMBL
ENST00000246657
,
ENSP00000246657
,
ENSG00000126353
OpenTargets
ENSG00000126353
GeneCards
CCR7
HPA
ENSG00000126353-CCR7
ZINC - Substances
CCR7_HUMAN
ZINC target
P32248
PRO
P32248
Pharos - Targets
P32248
GlyGen
P32248
PDB
6QZH
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