Reactome | SAP30L [nucleoplasm]

SAP30L [nucleoplasm]

Stable Identifier

R-HSA-351698

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

SP30L_HUMAN, Histone deacetylase complex subunit SAP30L

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - SARS-CoV Infections (Homo sapiens)
      - Potential therapeutics for SARS (Homo sapiens)
        
        HDAC1:2-containing complex binds HDAC2 Inhibitors (Homo sapiens)
        
        HDAC1:2-containing complex [nucleoplasm] (Homo sapiens)
        
        Sin3A complex [nucleoplasm] (Homo sapiens)
        
        SAP30L [nucleoplasm] (Homo sapiens)
        
        HDAC1:2-containing complex:HDAC2 inhibitors [nucleoplasm] (Homo sapiens)
        
        HDAC1:2-containing complex [nucleoplasm] (Homo sapiens)
        
        Sin3A complex [nucleoplasm] (Homo sapiens)
        
        SAP30L [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9HAJ7 SAP30L

Gene Names

SAP30L, NS4ATP2

Chain

chain:1-183

Reference Genes

BioGPS Gene:79685 SAP30L

COSMIC (genes):SAP30L SAP30L

CTD Gene:79685 SAP30L

dbSNP Gene:79685 SAP30L

ENSEMBL:ENSG00000164576 SAP30L

ENSEMBL_homo_sapiens_GENE:ENSG00000164576.12 SAP30L

HGNC:25663 SAP30L

KEGG Gene (Homo sapiens):79685 SAP30L

Monarch:79685 SAP30L

NCBI Gene:79685 SAP30L

OMIM:610398 SAP30L

UCSC:Q9HAJ7 SAP30L

Reference Transcript

Other Identifiers

11720376_a_at

11720377_s_at

11720378_a_at

11737711_a_at

16991374

219129_PM_s_at

219129_s_at

225509_PM_at

225509_at

2836664

2836666

2836667

2836668

2836669

2836670

2836671

2836676

2836681

2836685

2836686

2836687

2836688

2836690

56307_at

71085_at

79685

8109428

A_23_P368101

A_24_P191971

GE57027

GE80569

GO:0000118

GO:0000122

GO:0001650

GO:0003677

GO:0003712

GO:0005515

GO:0005634

GO:0005654

GO:0005730

GO:0006351

GO:0006355

GO:0008270

GO:0008289

GO:0010314

GO:0023052

GO:0030336

GO:0030512

GO:0031491

GO:0032266

GO:0042393

GO:0043226

GO:0044378

GO:0046872

GO:0048870

GO:0070273

GO:0140110

GO:1902455

GO:1902459

HMNXSV003003002

Hs.22350.0.S1_3p_at

Hs.22350.0.S1_3p_x_at

ILMN_1757781

ILMN_1843932

PH_hs_0022342

PH_hs_0039869

TC05000852.hg

TC05002703.hg

g13375861_3p_at

Participates

as a component of

Inferred To

Sap30l [nucleoplasm] (Mus musculus)

Sap30l [nucleoplasm] (Rattus norvegicus)

SAP30 [nucleoplasm] (Saccharomyces cerevisiae)

Ghost homologue of SAP30L [nucleoplasm] (Schizosaccharomyces pombe)

SAP30L [nucleoplasm] (Bos taurus)

SAP30L [nucleoplasm] (Canis familiaris)

SAP30L [nucleoplasm] (Dictyostelium discoideum)

SAP30L [nucleoplasm] (Gallus gallus)

SAP30L [nucleoplasm] (Sus scrofa)

Sap30 [nucleoplasm] (Drosophila melanogaster)

sap30l [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

NP_078908.1, NP_001124535.1, NP_001124534.1

OpenTargets

ENSG00000164576

GeneCards

Q9HAJ7

HPA

ENSG00000164576-SAP30L

Ensembl

ENST00000426761, ENSP00000297109, ENSP00000416393, ENSP00000390927, ENST00000440364, ENSG00000164576, ENST00000297109

PRO

Q9HAJ7

Pharos - Targets

Q9HAJ7

PDB

2N1U

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13547 HDAC1	2	HDAC1 [nucleoplasm] (R-HSA-205021) monoSUMO1-K444,K476-HDAC1 [nucleoplasm] (R-HSA-4616030)	0.725	6
UniProt:Q16576 RBBP7	1	RBBP7 [nucleoplasm] (R-HSA-212227)	0.643	5
UniProt:Q09028 RBBP4	1	RBBP4 [nucleoplasm] (R-HSA-212223)	0.527	4
UniProt:Q92769 HDAC2	2	monoSUMO1-K462-HDAC2 [nucleoplasm] (R-HSA-4615958) HDAC2 [nucleoplasm] (R-HSA-205135)	0.527	2
UniProt:Q9H160 ING2	2	monoSUMO1-K195-ING2 [nucleoplasm] (R-HSA-4086075) ING2 [nucleoplasm] (R-HSA-3215167)	0.527	3