dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine

Stable Identifier
R-HSA-351210
Type
Reaction
Species
Homo sapiens
Compartment
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The protein encoded by this gene belongs to the spermidine/spermine synthases family. This gene encodes an ubiquitous enzyme of polyamine metabolism. Defects in SMS are the cause of Snyder-Robinson syndrome (SRS).

Literature References
PubMed ID Title Journal Year
7546290 Molecular cloning of a cDNA encoding human spermine synthase

Keinänen, T, Korhonen, VP, Halmekytö, M, Alhonen, L, Myöhänen, S, Eloranta, T, Wahlfors, J, Kauppinen, L, Jänne, J, Hyvönen, T

DNA Cell Biol 1995
Participants
Participates
Catalyst Activity

spermine synthase activity of SMS [cytosol]

Orthologous Events
Cross References
Rhea
Authored
Reviewed
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