The PP2A complex that contains the regulatory subunit PPP2R2A (B55-alpha) is the only phosphatase essential for mitotic exit (Schmitz et al. 2010). It is also necessary for BANF1 (BAF) dephosphorylation in anaphase/telophase. ANKLE2 binds the PP2A complex that contains the B55-alpha regulatory subunit and facilitates BANF1 dephosphorylation (Asencio et al. 2012).
Asencio, C, Davidson, IF, Santarella-Mellwig, R, Ly-Hartig, TB, Mall, M, Wallenfang, MR, Mattaj, IW, Gorjánácz, M
Schmitz, MH, Held, M, Janssens, V, Hutchins, JR, Hudecz, O, Ivanova, E, Goris, J, Trinkle-Mulcahy, L, Lamond, AI, Poser, I, Hyman, AA, Mechtler, K, Peters, JM, Gerlich, DW
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