Reactome | AKR1B10 [cytosol]

AKR1B10 [cytosol]

Stable Identifier

R-HSA-2855246

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Aldo-keto reductase family 1 member B10 ecNumber1.1.1.-/ecNumber, AK1BA_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O60218 AKR1B10

Gene Names

AKR1B10, AKR1B11

Chain

chain:1-316

Reference Genes

BioGPS Gene:57016 AKR1B10

COSMIC (genes):AKR1B10 AKR1B10

CTD Gene:57016 AKR1B10

dbSNP Gene:57016 AKR1B10

ENSEMBL:ENSG00000198074 AKR1B10

HGNC:382 AKR1B10

KEGG:hsa:57016 AKR1B10

Monarch:57016 AKR1B10

NCBI Gene:57016 AKR1B10

OMIM:604707 AKR1B10

UCSC:O60218 AKR1B10

Reference Transcript

RefSeq:NM_020299.4 AKR1B10

Other Identifiers

11724488_at

11724489_s_at

11724490_x_at

11742378_a_at

17051827

206561_PM_s_at

206561_s_at

3025434

3025435

3025436

3025439

3025442

3025444

3025445

3025447

3025448

3025449

3025450

3025451

3025453

3025454

3025455

3025456

3025457

3025458

3025459

3025471

3025478

3025479

3025480

3025482

3249535

3249536

3249537

3249540

3249541

37482_at

57016

8136336

A_23_P93641

GE61082

GO:0001523

GO:0001758

GO:0003824

GO:0004032

GO:0004033

GO:0005515

GO:0005576

GO:0005739

GO:0005764

GO:0005773

GO:0005829

GO:0006629

GO:0008106

GO:0016488

GO:0016491

GO:0042572

GO:0043226

GO:0044597

GO:0044598

GO:0045550

GO:0047655

GO:0047718

GO:0052650

GO:0098754

GO:0110095

GO:1901135

HMNXSV003007171

HMNXSV003010412

HMNXSV003020143

ILMN_1672148

PH_hs_0006395

TC07000834.hg

TC07002600.hg

g13346507_3p_s_at

Participates

as a member of

AKRs [cytosol] (Homo sapiens)

Inferred To

LOC418170 [cytosol] (Gallus gallus)

akr [cytosol] (Gallus gallus)

ARY [cytosol] (Drosophila melanogaster)

Homologues of AKR1B10 [cytosol] (Caenorhabditis elegans)

Homologues of AKR1B10 [cytosol] (Danio rerio)

Homologues of AKR1B10 [cytosol] (Drosophila melanogaster)

Homologues of AKR1B10 [cytosol] (Gallus gallus)

AKR1B10 [cytosol] (Bos taurus)

AKR1B10 [cytosol] (Caenorhabditis elegans)

AKR1B10 [cytosol] (Danio rerio)

AKR1B10 [cytosol] (Drosophila melanogaster)

AKR1B10 [cytosol] (Gallus gallus)

AKR1B10 [cytosol] (Mus musculus)

AKR1B10 [cytosol] (Rattus norvegicus)

AKR1B10 [cytosol] (Xenopus tropicalis)

Cross References

OpenTargets

ENSG00000198074

ENSEMBL

ENSG00000198074, ENSP00000352584, ENST00000359579

ZINC - FDA approved

AK1BA_HUMAN

ZINC - Substances

AK1BA_HUMAN

ZINC - Biogenic

AK1BA_HUMAN

ZINC target

O60218

PRO

O60218

GlyGen

O60218

PDB

4XZL, 4JII, 5Y7N, 4GQ0, 4JIH, 4ICC, 5LIK, 5M2F, 4WEV, 4XZM, 4GAB, 4XZN, 1ZUA, 5LIX, 4I5X, 5LIY, 4GA8, 4GQG, 5LIW, 5LIU

ZINC - Investigational

AK1BA_HUMAN

ZINC - Metabolites

AK1BA_HUMAN

IntEnz

1.1.1.300

HPA

ENSG00000198074-AKR1B10

GeneCards

AKR1B10

Pharos - Targets

O60218

ZINC - Predictions - Purchasable

AK1BA_HUMAN

HMDB Protein

HMDBP11606

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13085 ACACA	2	Btn-ACACA [cytosol] (R-HSA-2976730) ACACA [cytosol] (R-HSA-1660609)	0.556	4
UniProt:P51857 AKR1D1	1	AKR1D1 [cytosol] (R-HSA-191975)	0.527	2
UniProt:C9JRZ8 AKR1B15	1	AKR1B15 [mitochondrial matrix] (R-HSA-5696834)	0.499	2