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FCN3 oligomer:MASP1 dimer:MASP2-1 dimer [extracellular region]
Stable Identifier
R-HSA-2855122
Type
Complex
Species
Homo sapiens
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Complement cascade (Homo sapiens)
Initial triggering of complement (Homo sapiens)
Creation of C4 and C2 activators (Homo sapiens)
Lectin pathway of complement activation (Homo sapiens)
Activation of MASPs (Homo sapiens)
MBL2,FCN:MASPs:carbohydrate patterns [plasma membrane] (Homo sapiens)
FCN3 ligands:FCN3 multimer:MASP1 dimer:MASP2 dimer:4xCa2+ [plasma membrane] (Homo sapiens)
FCN3 oligomer:MASP1 dimer:MASP2-1 dimer [extracellular region] (Homo sapiens)
Ficolins bind to repetitive carbohydrate structures on the target cell surface (Homo sapiens)
Ficolin-3 binds to molecular patterns on the target cell surface (Homo sapiens)
FCN3 ligands:FCN3 multimer:MASP1 dimer:MASP2 dimer:4xCa2+ [plasma membrane] (Homo sapiens)
FCN3 oligomer:MASP1 dimer:MASP2-1 dimer [extracellular region] (Homo sapiens)
FCN3 oligomer:MASP1 dimer:MASP2-1 dimer [extracellular region] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
18596036
Crystal structure of the CUB1-EGF-CUB2 domain of human MASP-1/3 and identification of its interaction sites with mannan-binding lectin and ficolins
Martin, L
,
Teillet, F
,
Arlaud, GJ
,
Lacroix, M
,
Gaboriaud, C
,
Thielens, NM
J Biol Chem
2008
Participants
components
FCN3 oligomer [extracellular region]
(Homo sapiens)
MASP1 dimer [extracellular region]
(Homo sapiens)
MASP2-1 dimer [extracellular region]
(Homo sapiens)
Participates
as an input of
Ficolin-3 binds to molecular patterns on the target cell surface (Homo sapiens)
as a component of
FCN3 ligands:FCN3 multimer:MASP1 dimer:MASP2 dimer:4xCa2+ [plasma membrane] (Homo sapiens)
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