Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
5-sulfiliminyl collagen alpha-5(IV) chain [extracellular region]
Stable Identifier
R-HSA-2682384
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Collagen formation (Homo sapiens)
Assembly of collagen fibrils and other multimeric structures (Homo sapiens)
Crosslinking of collagen fibrils (Homo sapiens)
Collagen type IV sulfilimine cross-linking by peroxidasin (Homo sapiens)
Collagen type IV networks with sulfilimine cross-links [extracellular region] (Homo sapiens)
Sulfilimine-containing collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Homo sapiens)
Collagen type IV alpha1.alpha2.alpha5.alpha6 tropocollagens with or without sulfilimine cross-links [extracellular region] (Homo sapiens)
Tropocollagen alpha-5(IV).alpha-5(IV).alpha-6(IV) with or without sulfilimine cross-links [extracellular region] (Homo sapiens)
Sulfiliminyl tropocollagen alpha-5(IV).alpha-5(IV).alpha-6(IV) [extracellular region] (Homo sapiens)
Sulfiliminyl collagen alpha-5(IV) chains [extracellular region] (Homo sapiens)
5-sulfiliminyl collagen alpha-5(IV) chain [extracellular region] (Homo sapiens)
Sulfilimine-containing collagen type IV alpha3.alpha4.alpha5 network [extracellular region] (Homo sapiens)
Tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) with or without sulfilimine cross-links [extracellular region] (Homo sapiens)
Sulfiliminyl tropocollagen alpha-3(IV).alpha-4(IV).alpha-5(IV) [extracellular region] (Homo sapiens)
Sulfiliminyl collagen alpha-5(IV) chains [extracellular region] (Homo sapiens)
5-sulfiliminyl collagen alpha-5(IV) chain [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P29400 COL4A5
Gene Names
COL4A5
Chain
signal peptide:1-26, chain:27-1685
Reference Genes
BioGPS Gene:1287 COL4A5
COSMIC (genes):COL4A5 COL4A5
CTD Gene:1287 COL4A5
dbSNP Gene:1287 COL4A5
ENSEMBL:ENSG00000188153 COL4A5
HGNC:2207 COL4A5
KEGG:hsa:1287 COL4A5
Monarch:1287 COL4A5
NCBI Gene:1287 COL4A5
OMIM:303630 COL4A5
UCSC:P29400 COL4A5
Reference Transcript
RefSeq:NM_000495.5 COL4A5
RefSeq:NM_033380.3 COL4A5
Participates
as a member of
Sulfiliminyl collagen alpha-5(IV) chains [extracellular region] (Homo sapiens)
Other forms of this molecule
3x4Hyp-3Hyp-GlcGalHyl-COL4A5 [endoplasmic reticulum lumen]
GlcGalHyl-COL4A5 [endoplasmic reticulum lumen]
3x4Hyp-GlcGalHyl-COL4A5 [endoplasmic reticulum lumen]
GalHyl-COL4A5 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GalHyl-COL4A5 [endoplasmic reticulum lumen]
3x4Hyp-GalHyl-COL4A5 [endoplasmic reticulum lumen]
COL4A5 [endoplasmic reticulum lumen]
3x4Hyp-COL4A5 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-COL4A5 [endoplasmic reticulum lumen]
3x4Hyp-5Hyl-COL4A5 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-5Hyl-COL4A5 [endoplasmic reticulum lumen]
5Hyl-COL4A5 [endoplasmic reticulum lumen]
3,4-Hyp 5-sulfiliminyl collagen alpha-5(IV) chain [extracellular region]
3x4Hyp-GalHyl-COL4A5 [extracellular region]
3x4Hyp-3Hyp-COL4A5 [extracellular region]
3x4Hyp-GlcGalHyl-COL4A5 [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A5 [extracellular region]
5Hyl-COL4A5 [extracellular region]
3x4Hyp-5Hyl-COL4A5 [extracellular region]
3x4Hyp-COL4A5 [extracellular region]
GlcGalHyl-COL4A5 [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A5 [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A5 [extracellular region]
COL4A5 [extracellular region]
GalHyl-COL4A5 [extracellular region]
COL4A5(27-?) [extracellular region]
5Hyl-COL4A5(27-?) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A5(?-1685) [extracellular region]
3x4Hyp-GalHyl-COL4A5(?-1685) [extracellular region]
3x4Hyp-5Hyl-COL4A5(27-?) [extracellular region]
GlcGalHyl-COL4A5(?-1685) [extracellular region]
3x4Hyp-3Hyp-COL4A5(27-?) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A5(?-1685) [extracellular region]
5Hyl-COL4A5(?-1685) [extracellular region]
3x4Hyp-GlcGalHyl-COL4A5(27-?) [extracellular region]
3x4Hyp-COL4A5(?-1685) [extracellular region]
GalHyl-COL4A5(?-1685) [extracellular region]
3x4Hyp-3Hyp-COL4A5(?-1685) [extracellular region]
COL4A5(27-?) [extracellular region]
3x4Hyp-GalHyl-COL4A5(27-?) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A5(27-?) [extracellular region]
GalHyl-COL4A5(27-?) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A5(27-?) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A5(?-1685) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A5(27-?) [extracellular region]
3x4Hyp-COL4A5(27-?) [extracellular region]
COL4A5(?-1685) [extracellular region]
3x4Hyp-GlcGalHyl-COL4A5(?-1685) [extracellular region]
3x4Hyp-5Hyl-COL4A5(?-1685) [extracellular region]
GlcGalHyl-COL4A5(27-?) [extracellular region]
4-Hyp 5-sulfiliminyl collagen alpha-5(IV) chain [extracellular region]
Inferred To
Col4a5 [extracellular region]
(Mus musculus)
Col4a5 [extracellular region]
(Rattus norvegicus)
emb-9 [extracellular region]
(Caenorhabditis elegans)
5-sulfiliminyl collagen alpha-5(IV) chain [extracellular region]
(Bos taurus)
COL4A5 [extracellular region]
(Canis familiaris)
COL4A5 [extracellular region]
(Gallus gallus)
COL4A5 [extracellular region]
(Sus scrofa)
col7a1 [extracellular region]
(Xenopus tropicalis)
Modified Residues
Name
(2S,5R)-5-hydroxylysine (sulfilimine bond) at unknown position
Modification
sulfilimine bond
PsiMod Name
(2S,5R)-5-hydroxylysine
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to 5-hydroxy-L-lysine.
Cross References
RefSeq
NP_203699.1
,
NP_000486.1
OpenTargets
ENSG00000188153
ENSEMBL
ENST00000361603
,
ENSP00000331902
,
ENSG00000188153
,
ENSP00000354505
,
ENST00000328300
GeneCards
COL4A5
HPA
ENSG00000188153-COL4A5
PRO
P29400
Pharos - Targets
P29400
GlyGen
P29400
Orphanet
COL4A5
PDB
5NAZ
,
6WKU
© 2025
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
