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SGK3 [cytosol]
Stable Identifier
R-HSA-2682351
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Serine/threonine-protein kinase Sgk3 ecNumber2.7.11.1/ecNumber, SGK3_HUMAN
Locations in the PathwayBrowser
Expand all
Transport of small molecules (Homo sapiens)
Ion channel transport (Homo sapiens)
Stimuli-sensing channels (Homo sapiens)
RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels (Homo sapiens)
RAF1:SGK:TSC22D3:WPP [cytosol] (Homo sapiens)
SGK1/2/3 [cytosol] (Homo sapiens)
SGK3 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96BR1 SGK3
Gene Names
SGK3, CISK, SGKL
Chain
chain:1-496
Reference Genes
BioGPS Gene:100533105 SGK3
BioGPS Gene:23678 SGK3
COSMIC (genes):SGK3 SGK3
CTD Gene:100533105 SGK3
CTD Gene:23678 SGK3
dbSNP Gene:100533105 SGK3
dbSNP Gene:23678 SGK3
ENSEMBL:ENSG00000104205 SGK3
HGNC:10812 SGK3
KEGG Gene (Homo sapiens):100533105 SGK3
KEGG Gene (Homo sapiens):23678 SGK3
Monarch:100533105 SGK3
Monarch:23678 SGK3
NCBI Gene:100533105 SGK3
NCBI Gene:23678 SGK3
OMIM:607591 SGK3
UCSC:Q96BR1 SGK3
Reference Transcript
RefSeq:NM_001204173.1 SGK3
RefSeq:NM_001033578.2 SGK3
RefSeq:NM_170709.2 SGK3
RefSeq:NM_013257.4 SGK3
Other Identifiers
0001780373
0001780435
100533105
11724103_x_at
11724104_s_at
11724105_a_at
17069605
220038_3p_at
220038_at
227627_at
23678
243264_s_at
3101766
3101780
3101781
3101795
3101803
3101812
3101815
3101816
3101817
3101819
3101821
3101822
3101826
3101827
3101829
3101830
3101832
3101834
3101837
3101840
3101842
3101843
3101845
3101849
3101850
43535_at
8146717
82429_s_at
A_24_P46953
A_33_P3375613
GE62958
GO:0000166
GO:0001558
GO:0003674
GO:0004672
GO:0004674
GO:0005246
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005768
GO:0005769
GO:0005829
GO:0006464
GO:0006468
GO:0006810
GO:0007165
GO:0008150
GO:0008283
GO:0008289
GO:0009058
GO:0015459
GO:0016301
GO:0016310
GO:0016740
GO:0017080
GO:0017081
GO:0018105
GO:0030334
GO:0031410
GO:0034220
GO:0034641
GO:0035091
GO:0035556
GO:0040007
GO:0040011
GO:0042127
GO:0043167
GO:0043226
GO:0043231
GO:0048870
GO:0051090
GO:0055037
GO:0055085
Hs.160795.0.A1_3p_s_at
Hs.24131.0.S1_3p_at
ILMN_1729785
ILMN_1747020
ILMN_2366703
PH_hs_0018553
TC08002607.hg
g7019526_3p_at
Participant Of
hasMember
SGK1/2/3 [cytosol]
Inferred To
SGK3 [cytosol] (Canis familiaris)
SGK3 [cytosol] (Gallus gallus)
SGK3 [cytosol] (Xenopus tropicalis)
sgk-1 [cytosol] (Caenorhabditis elegans)
Sgk3 [cytosol] (Mus musculus)
Sgk3 [cytosol] (Rattus norvegicus)
Cross References
RefSeq
NP_001028750.1
,
NP_733827.2
,
NP_001191102.1
,
NP_037389.4
ZINC - World Drugs
SGK3_HUMAN
OpenTargets
ENSG00000104205
ZINC - FDA approved
SGK3_HUMAN
ZINC - Substances
SGK3_HUMAN
ZINC target
Q96BR1
ZINC - Biogenic
SGK3_HUMAN
PRO
Q96BR1
PDB
6EDX
ZINC - Investigational
SGK3_HUMAN
HPA
ENSG00000104205-SGK3
GeneCards
Q96BR1
Ensembl
ENSG00000288602
,
ENSG00000104205
,
ENST00000522398
,
ENST00000519289
,
ENST00000521198
,
ENSP00000331816
,
ENSP00000379842
,
ENSP00000430691
,
ENSP00000430463
,
ENST00000345714
,
ENST00000396596
,
ENST00000520976
,
ENSP00000429022
,
ENSP00000430256
ZINC - Predictions - Purchasable
SGK3_HUMAN
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96J02 ITCH
1
ITCH [cytosol]
(R-HSA-975995)
0.645
5
1-phosphatidyl-1D-myo-inositol 3-phosphate [ChEBI:17283]
6
PI3P [late endosome membrane]
(R-ALL-1806198)
PI3P [cytosol]
(R-ALL-1629751)
PI3P [early endosome membrane]
(R-ALL-1806200)
PI3P [Golgi membrane]
(R-ALL-1806159)
PI3P [plasma membrane]
(R-ALL-1806276)
PI3P [phagophore assembly site membrane]
(R-ALL-5693050)
0.602
4
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