Ub-C871-ITCH [cytosol]

Stable Identifier
R-HSA-8864515
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
E3 ubiquitin-protein ligase Itchy homolog, ITCH_HUMAN
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:Q96J02 ITCH
Gene Names
ITCH
Chain
initiator methionine:, chain:2-903
Reference Genes
BioGPS Gene:83737 ITCH
COSMIC (genes):ITCH ITCH
CTD Gene:83737 ITCH
dbSNP Gene:83737 ITCH
ENSEMBL:ENSG00000078747 ITCH
ENSEMBL_homo_sapiens_GENE:ENSG00000078747.17 ITCH
HGNC:13890 ITCH
KEGG Gene (Homo sapiens):83737 ITCH
Monarch:83737 ITCH
NCBI Gene:83737 ITCH
OMIM:606409 ITCH
UCSC:Q96J02 ITCH
Reference Transcript
Other Identifiers
11731493_at
11731494_a_at
11745275_x_at
11749666_a_at
16912905
209743_PM_s_at
209743_s_at
209744_PM_x_at
209744_x_at
217094_PM_s_at
217094_s_at
235057_PM_at
235057_at
239101_PM_at
239101_at
38349_at
3882855
3882858
3882862
3882863
3882867
3882871
3882873
3882875
3882877
3882884
3882885
3882886
3882887
3882889
3882891
3882892
3882893
3882898
3882901
3882906
3882909
3882910
3882911
3882912
3882915
3882917
3882918
3882921
3882923
3882924
3882925
3882926
3882927
3882928
3882929
3882946
3882948
46555_at
74663_s_at
74996_at
76200_r_at
8061986
83737
88659_at
A_14_P109028
A_14_P121685
A_14_P128989
A_24_P139191
GE61516
GO:0000209
GO:0001558
GO:0002376
GO:0002669
GO:0002870
GO:0003824
GO:0004842
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0005768
GO:0005769
GO:0005829
GO:0005886
GO:0005938
GO:0006351
GO:0006355
GO:0006511
GO:0006513
GO:0006915
GO:0006954
GO:0007155
GO:0010008
GO:0012501
GO:0016020
GO:0016192
GO:0016567
GO:0016740
GO:0016874
GO:0019787
GO:0023052
GO:0030154
GO:0030163
GO:0031410
GO:0031623
GO:0031901
GO:0032088
GO:0032480
GO:0032991
GO:0035519
GO:0035739
GO:0036211
GO:0039532
GO:0043021
GO:0043066
GO:0043161
GO:0043226
GO:0043231
GO:0044389
GO:0045087
GO:0045236
GO:0045732
GO:0046329
GO:0046718
GO:0048856
GO:0050687
GO:0051607
GO:0051865
GO:0060544
GO:0061630
GO:0070062
GO:0070423
GO:0070534
GO:0070936
GO:0090085
GO:0098542
GO:0140096
GO:1902036
GO:1990763
GO:2000562
GO:2000646
HMNXSV003038485
HMNXSV003044003
Hs.120212.0.A1_3p_at
Hs.134350.0.A1_3p_at
Hs.98074.0.S1_3p_a_at
Hs.98074.1.S1_3p_a_at
ILMN_1752283
PH_hs_0023754
TC20000239.hg
Other forms of this molecule
ITCH [cytosol]
Inferred To
ITCH [cytosol] (Bos taurus)
Ub-C871-ITCH [cytosol] (Sus scrofa)
Itch [cytosol] (Mus musculus)
Itch [cytosol] (Rattus norvegicus)
Modified Residues
Name
S-(glycyl)-L-cysteine (Cys-Gly) at 871
Coordinate
871
PsiMod Name
S-(glycyl)-L-cysteine (Cys-Gly)
PsiMod Definition
A protein modification that effectively crosslinks an L-cysteine residue and a glycine residue by a thioester bond to form S-glycyl-L-cysteine.
Cross References
RefSeq
OpenTargets
GeneCards
HPA
Ensembl
PRO
Pharos - Targets
Orphanet
HMDB Protein
PDB
Interactors (32)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q96B67 ARRD3      0.768 5
 UniProt:O15350 TP73  3 0.75 5
 UniProt:Q8N5I2 ARRD1      0.738 5
 UniProt:Q9NW97 TMM51      0.688 4
 UniProt:Q15884 EREP1      0.659 4
 UniProt:Q96BR1 SGK3  1 0.645 5
 UniProt:Q8N0X7 SPART      0.643 3
 UniProt:O15350-1 TP73      0.639 5
 UniProt:Q9Y5X1 SNX9  3 0.623 7
 UniProt:P13569 CFTR  17 0.615 15
 UniProt:Q9ULV8 CBLC      0.602 5
 UniProt:P08151 GLI1  9 0.602 4
 UniProt:O75113 N4BP1  3 0.591 3
 UniProt:P13285 LMP2      0.59 3
 UniProt:Q16655 MLANA  1 0.59 2
 UniProt:Q14511 CASL      0.581 3
 UniProt:Q9BTU6 PI4K2A  1 0.571 5
 UniProt:Q96BY9 SARAF      0.564 2
 UniProt:Q9Y3C5 RNF11      0.544 2
 UniProt:Q8NCT1 ARRD4      0.527 2
 UniProt:Q6UXU6 TMM92      0.527 2
 UniProt:Q5JRV8 T255A      0.527 2
 UniProt:Q96G27 WBP1      0.527 2
 UniProt:Q8WVE6 TM171      0.527 2
 UniProt:Q9H0M0 WWP1  1 0.527 2
 UniProt:O75791 GRAP2  1 0.527 2
 UniProt:Q99962 SH3GL2  4 0.526 3
 UniProt:Q9QZS3-2 NUMB      0.524 2
 UniProt:Q9H3D4 TP63  1 0.499 2
 UniProt:P70444  4 0.471 2
 UniProt:Q86Y01 DTX1  1 0.463 2
 UniProt:Q9EPK8 Trpv4  1 0.463 2
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