Reactome | DAD1 [endoplasmic reticulum membrane]

DAD1 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-265089

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Dad1

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - SARS-CoV Infections (Homo sapiens)
      - SARS-CoV-2 Infection (Homo sapiens)
        
        Late SARS-CoV-2 Infection Events (Homo sapiens)
        
        Translation of Structural Proteins (Homo sapiens)
        
        Maturation of spike protein (Homo sapiens)
        
        Spike protein gets N-glycosylated (Homo sapiens)
        
        OST complex [endoplasmic reticulum membrane] (Homo sapiens)
        
        OST-A [endoplasmic reticulum membrane] (Homo sapiens)
        
        OST Subcomplex III [endoplasmic reticulum membrane] (Homo sapiens)
        
        DAD1 [endoplasmic reticulum membrane] (Homo sapiens)
        
        OST-B [endoplasmic reticulum membrane] (Homo sapiens)
        
        OST Subcomplex III [endoplasmic reticulum membrane] (Homo sapiens)
        
        DAD1 [endoplasmic reticulum membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P61803 DAD1

Gene Names

DAD1

Chain

initiator methionine:, chain:2-113

Reference Genes

BioGPS Gene:1603 DAD1

COSMIC (genes):DAD1 DAD1

CTD Gene:1603 DAD1

dbSNP Gene:1603 DAD1

ENSEMBL:ENSG00000129562 DAD1

HGNC:2664 DAD1

KEGG:hsa:1603 DAD1

Monarch:1603 DAD1

NCBI Gene:1603 DAD1

OMIM:600243 DAD1

UCSC:P61803 DAD1

Reference Transcript

RefSeq:NM_001344.3 DAD1

Other Identifiers

11720317_a_at

11754060_a_at

11757687_x_at

1603

16790464

18671151

18671152

18671153

18671154

18671155

18671157

18671158

200046_PM_at

200046_at

3556570

3556571

3556574

3556580

3556581

3556588

3556589

3556590

38413_at

7892663

7892704

7895246

7896653

7977775

A_23_P106056

A_24_P47870

A_24_P56462

D15057_at

GE79876

GO:0001824

GO:0005783

GO:0005789

GO:0006486

GO:0006487

GO:0006915

GO:0008047

GO:0008250

GO:0012501

GO:0016020

GO:0018279

GO:0031647

GO:0043066

GO:0043226

GO:0048856

GO:0098772

HMNXSV003012164

ILMN_1731619

PH_hs_0004740

TC14000931.hg

g4503252_3p_s_at

Participates

as a component of

OST Subcomplex III [endoplasmic reticulum membrane] (Homo sapiens)

Cross References

RefSeq

NP_001335.1

ENSEMBL

ENST00000250498, ENSP00000250498, ENSG00000129562

OpenTargets

ENSG00000129562

GeneCards

DAD1

HPA

ENSG00000129562-DAD1

PRO

P61803

Pharos - Targets

P61803

GlyGen

P61803

HMDB Protein

HMDBP03268

PDB

8PN9, 8B6L, 6S7T, 6S7O

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8TCJ2 STT3B	1	STT3B [endoplasmic reticulum membrane] (R-HSA-264930)	0.528	2
UniProt:Q14165 MLEC	3	MLEC [endoplasmic reticulum membrane] (R-HSA-901082) MLEC [plasma membrane] (R-HSA-6806292) MLEC [specific granule membrane] (R-HSA-6799618)	0.528	2
UniProt:P23945 FSHR	1	FSHR [plasma membrane] (R-HSA-391380)	0.527	2