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GlcGalHyl-COL8A1(?-744) [extracellular region]
Stable Identifier
R-HSA-2470373
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Glu-Gal-Hyl-collagen alpha-1(VIII) chain C-term fragment
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Degradation of the extracellular matrix (Homo sapiens)
Collagen degradation (Homo sapiens)
Collagen type VIII degradation by ELANE (Homo sapiens)
Cleaved collagen type VIII fibril [extracellular region] (Homo sapiens)
Cleaved tropocollagen type VIII [extracellular region] (Homo sapiens)
Cleaved collagen alpha-1(VIII) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL8A1(?-744) [extracellular region] (Homo sapiens)
Collagen type VIII degradation by MMP1 (Homo sapiens)
Cleaved collagen type VIII fibril [extracellular region] (Homo sapiens)
Cleaved tropocollagen type VIII [extracellular region] (Homo sapiens)
Cleaved collagen alpha-1(VIII) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL8A1(?-744) [extracellular region] (Homo sapiens)
Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 (Homo sapiens)
Cleaved collagen fibrils [extracellular region] (Homo sapiens)
Cleaved collagen type VIII fibril [extracellular region] (Homo sapiens)
Cleaved tropocollagen type VIII [extracellular region] (Homo sapiens)
Cleaved collagen alpha-1(VIII) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL8A1(?-744) [extracellular region] (Homo sapiens)
Gelatin degradation by MMP19 (Homo sapiens)
Cleaved collagen fibrils [extracellular region] (Homo sapiens)
Cleaved collagen type VIII fibril [extracellular region] (Homo sapiens)
Cleaved tropocollagen type VIII [extracellular region] (Homo sapiens)
Cleaved collagen alpha-1(VIII) chains [extracellular region] (Homo sapiens)
GlcGalHyl-COL8A1(?-744) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P27658 COL8A1
Gene Names
COL8A1, C3orf7
Chain
signal peptide:1-27, chain:28-744, chain:572-744
Reference Genes
BioGPS Gene:1295 COL8A1
COSMIC (genes):COL8A1 COL8A1
CTD Gene:1295 COL8A1
dbSNP Gene:1295 COL8A1
ENSEMBL:ENSG00000144810 COL8A1
ENSEMBL_homo_sapiens_GENE:ENSG00000144810.16 COL8A1
HGNC:2215 COL8A1
KEGG Gene (Homo sapiens):1295 COL8A1
Monarch:1295 COL8A1
NCBI Gene:1295 COL8A1
OMIM:120251 COL8A1
UCSC:P27658 COL8A1
Reference Transcript
RefSeq:NM_020351.3 COL8A1
RefSeq:NM_001850.4 COL8A1
Other Identifiers
11728809_a_at
1295
214587_PM_at
214587_at
226237_PM_at
226237_at
2633400
2633401
2633410
2633432
2633440
2633441
2633442
2633443
2633444
2633445
2633446
2633447
2633448
37459_at
52019_at
71929_at
85126_at
A_14_P129689
A_14_P134616
A_23_P211762
A_23_P69030
A_24_P139152
GE59827
GE79165
GO:0001525
GO:0001935
GO:0005198
GO:0005515
GO:0005576
GO:0005581
GO:0005591
GO:0005604
GO:0005615
GO:0005783
GO:0005788
GO:0007155
GO:0010811
GO:0030020
GO:0030154
GO:0030198
GO:0030312
GO:0031012
GO:0035987
GO:0043226
GO:0048593
GO:0048856
GO:0062023
HMNXSV003050033
Hs.114599.0.S2_3p_at
Hs.41271.0.S1_3p_at
ILMN_1685433
ILMN_2246563
ILMN_2402392
PH_hs_0006297
TC03000502.hg
Participates
as a member of
Cleaved collagen alpha-1(VIII) chains [extracellular region] (Homo sapiens)
Other forms of this molecule
3x4Hyp-3Hyp-GalHyl-COL8A1(28-744) [endoplasmic reticulum lumen]
GalHyl-COL8A1(28-744) [endoplasmic reticulum lumen]
3x4Hyp-GalHyl-COL8A1(28-744) [endoplasmic reticulum lumen]
3x4Hyp-GlcGalHyl-COL8A1(28-744) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GlcGalHyl-COL8A1(28-744) [endoplasmic reticulum lumen]
GlcGalHyl-COL8A1(28-744) [endoplasmic reticulum lumen]
COL8A1(28-744) [endoplasmic reticulum lumen]
3x4Hyp-COL8A1(28-744) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-COL8A1(28-744) [endoplasmic reticulum lumen]
3x4Hyp-5Hyl-COL8A1(28-744) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-5Hyl-COL8A1(28-744) [endoplasmic reticulum lumen]
5Hyl-COL8A1(28-744) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-COL8A1(28-?) [extracellular region]
GalHyl-COL8A1(?-744) [extracellular region]
3x4Hyp-3Hyp-COL8A1(?-744) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL8A1(?-744) [extracellular region]
3x4Hyp-5Hyl-COL8A1(?-744) [extracellular region]
GalHyl-COL8A1(28-?) [extracellular region]
5Hyl-COL8A1(?-744) [extracellular region]
COL8A1(?-744) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL8A1(28-?) [extracellular region]
3x4Hyp-5Hyl-COL8A1(28-?) [extracellular region]
GlcGalHyl-COL8A1(28-?) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL8A1(?-744) [extracellular region]
3x4Hyp-GalHyl-COL8A1(28-?) [extracellular region]
5Hyl-COL8A1(28-?) [extracellular region]
3x4Hyp-COL8A1(28-?) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL8A1(?-744) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL8A1(28-?) [extracellular region]
COL8A1(28-?) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL8A1(28-?) [extracellular region]
3x4Hyp-GalHyl-COL8A1(?-744) [extracellular region]
3x4Hyp-GlcGalHyl-COL8A1(?-744) [extracellular region]
GalHyl-COL8A1(28-744) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL8A1(28-744) [extracellular region]
COL8A1(28-744) [extracellular region]
5Hyl-COL8A1(28-744) [extracellular region]
3x4Hyp-3Hyp-COL8A1(28-744) [extracellular region]
3x4Hyp-GlcGalHyl-COL8A1(28-744) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL8A1(28-744) [extracellular region]
3x4Hyp-COL8A1(?-744) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL8A1(28-744) [extracellular region]
3x4Hyp-GalHyl-COL8A1(28-744) [extracellular region]
GlcGalHyl-COL8A1(28-744) [extracellular region]
3x4Hyp-5Hyl-COL8A1(28-744) [extracellular region]
3x4Hyp-GlcGalHyl-COL8A1(28-?) [extracellular region]
Inferred To
col-99 [extracellular region]
(Caenorhabditis elegans)
GlcGalHyl-COL8A1(?-744) [extracellular region]
(Gallus gallus)
GlcGalHyl-COL8A1(?-744) [extracellular region]
(Sus scrofa)
CMSS1 [extracellular region]
(Canis familiaris)
Col8a1 [extracellular region]
(Mus musculus)
Col8a1 [extracellular region]
(Rattus norvegicus)
Mp [extracellular region]
(Drosophila melanogaster)
COL8A1 [extracellular region]
(Bos taurus)
Modified Residues
Name
O5-glucosylgalactosyl-L-hydroxylysine at unknown position
PsiMod Name
O5-glucosylgalactosyl-L-hydroxylysine
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to O5-glucosylgalactosyl-L-hydroxylysine.
Cross References
RefSeq
NP_001841.2
,
NP_065084.2
OpenTargets
ENSG00000144810
GeneCards
P27658
HPA
ENSG00000144810-COL8A1
Ensembl
ENSP00000261037
,
ENST00000273342
,
ENSP00000273342
,
ENSP00000498483
,
ENST00000652472
,
ENSG00000144810
,
ENST00000261037
PRO
P27658
Pharos - Targets
P27658
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O43559 FRS3
3
p-5Y-FRS3 [plasma membrane]
(R-HSA-191475)
FRS3 [plasma membrane]
(R-HSA-191482)
p-Y-FRS3 [plasma membrane]
(R-HSA-9032427)
0.556
3
UniProt:P49639 HOXA1
1
HOXA1 [nucleoplasm]
(R-HSA-5617464)
0.556
6
UniProt:Q12837 POU4F2
1
POU4F2 [nucleoplasm]
(R-HSA-6804414)
0.556
5
UniProt:O76003 GLRX3
1
GLRX3 [cytosol]
(R-HSA-5691202)
0.556
3
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