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SREBP1A,1C,2:NF-Y:HMGCS1 gene [nucleoplasm]
Stable Identifier
R-HSA-2426129
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
SREBF1A,1C,2:NF-Y:HMGCS1 gene
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Regulation of cholesterol biosynthesis by SREBP (SREBF) (Homo sapiens)
Activation of gene expression by SREBF (SREBP) (Homo sapiens)
Expression of Hydroxymethylglutaryl coenzyme A synthase (HMGCS1) (Homo sapiens)
SREBP1A,1C,2:NF-Y:HMGCS1 gene [nucleoplasm] (Homo sapiens)
SREBP1A,1C,2 binds the HMGCS1 promoter (Homo sapiens)
SREBP1A,1C,2:NF-Y:HMGCS1 gene [nucleoplasm] (Homo sapiens)
Regulation of lipid metabolism by PPARalpha (Homo sapiens)
PPARA activates gene expression (Homo sapiens)
Expression of Hydroxymethylglutaryl coenzyme A synthase (HMGCS1) (Homo sapiens)
SREBP1A,1C,2:NF-Y:HMGCS1 gene [nucleoplasm] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
18654640
Genome-wide occupancy of SREBP1 and its partners NFY and SP1 reveals novel functional roles and combinatorial regulation of distinct classes of genes
Szekely, AM
,
Weissman, SM
,
Reed, BD
,
Snyder, M
,
Charos, AE
PLoS Genet
2008
Participants
components
HMGCS1 gene [nucleoplasm]
(Homo sapiens)
NF-Y [nucleoplasm]
(Homo sapiens)
SREBP1A,1C,2 dimer [nucleoplasm]
(Homo sapiens)
Participates
as an output of
SREBP1A,1C,2 binds the HMGCS1 promoter (Homo sapiens)
This entity regulates
Positively
Expression of Hydroxymethylglutaryl coenzyme A synthase (HMGCS1)
(Homo sapiens)
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