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PIK3CA helical domain mutants [cytosol]
Stable Identifier
R-HSA-2399587
Type
Set [CandidateSet]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
PI3K/AKT Signaling in Cancer (Homo sapiens)
Constitutive Signaling by Aberrant PI3K in Cancer (Homo sapiens)
PI3K gain of function mutants phosphorylate PIP2 to PIP3 (Homo sapiens)
PI3K mutants [plasma membrane] (Homo sapiens)
PIK3R1:PIK3CA mutants [plasma membrane] (Homo sapiens)
PIK3CA mutants [cytosol] (Homo sapiens)
PIK3CA helical domain mutants [cytosol] (Homo sapiens)
PI3K inhibitors block PI3K catalytic activity (Homo sapiens)
PI3K Inhibitors:PI3K [cytosol] (Homo sapiens)
PI3K mutants,Activator:PI3K [plasma membrane] (Homo sapiens)
PI3K mutants [plasma membrane] (Homo sapiens)
PIK3R1:PIK3CA mutants [plasma membrane] (Homo sapiens)
PIK3CA mutants [cytosol] (Homo sapiens)
PIK3CA helical domain mutants [cytosol] (Homo sapiens)
PI3K mutants,Activator:PI3K [plasma membrane] (Homo sapiens)
PI3K mutants [plasma membrane] (Homo sapiens)
PIK3R1:PIK3CA mutants [plasma membrane] (Homo sapiens)
PIK3CA mutants [cytosol] (Homo sapiens)
PIK3CA helical domain mutants [cytosol] (Homo sapiens)
Participants
members
PIK3CA E542K [cytosol]
(Homo sapiens)
PIK3CA E545K [cytosol]
(Homo sapiens)
PIK3CA E545A [cytosol]
(Homo sapiens)
PIK3CA Q546K [cytosol]
(Homo sapiens)
candidates
PIK3CA E542Q [cytosol]
(Homo sapiens)
PIK3CA E542V [cytosol]
(Homo sapiens)
PIK3CA E545G [cytosol]
(Homo sapiens)
PIK3CA E545Q [cytosol]
(Homo sapiens)
PIK3CA E545V [cytosol]
(Homo sapiens)
PIK3CA Q546E [cytosol]
(Homo sapiens)
PIK3CA Q546H [cytosol]
(Homo sapiens)
PIK3CA Q546L [cytosol]
(Homo sapiens)
PIK3CA Q546P [cytosol]
(Homo sapiens)
PIK3CA Q546R [cytosol]
(Homo sapiens)
Participates
as a member of
PIK3CA mutants [cytosol] (Homo sapiens)
Disease
Name
Identifier
Synonyms
cancer
DOID:162
malignant tumor, malignant neoplasm, primary cancer
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