Reactome | USP15 [cytosol]

USP15 [cytosol]

Stable Identifier

R-HSA-2173138

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Ubiquitin carboxyl-terminal hydrolase 15

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9Y4E8 USP15

Gene Names

USP15, KIAA0529

Chain

initiator methionine:1, chain:2-981

Reference Genes

BioGPS Gene:9958 USP15

COSMIC (genes):USP15 USP15

CTD Gene:9958 USP15

dbSNP Gene:9958 USP15

ENSEMBL:ENSG00000135655 USP15

HGNC:12613 USP15

KEGG:hsa:9958 USP15

Monarch:9958 USP15

NCBI Gene:9958 USP15

OMIM:604731 USP15

UCSC:Q9Y4E8 USP15

Reference Transcript

Participates

as a component of

as a member of

UCHL5/USP15 [cytosol] (Homo sapiens)

Inferred To

usp-4 [cytosol] (Caenorhabditis elegans)

USP15 [cytosol] (Bos taurus)

USP15 [cytosol] (Canis familiaris)

USP15 [cytosol] (Gallus gallus)

USP15 [cytosol] (Sus scrofa)

Homologues of USP15 [cytosol] (Caenorhabditis elegans)

Usp15 [cytosol] (Mus musculus)

Usp15 [cytosol] (Rattus norvegicus)

Ghost homologue of USP15 [cytosol] (Danio rerio)

Ghost homologue of USP15 [cytosol] (Drosophila melanogaster)

usp15 [cytosol] (Xenopus tropicalis)

usp-50 [cytosol] (Caenorhabditis elegans)

Cross References

RefSeq

NP_006304.1, NP_001239007.1, NP_001239008.1

OpenTargets

ENSG00000135655

ENSEMBL

ENST00000353364, ENSP00000309240, ENSP00000280377, ENSP00000258123, ENSG00000135655, ENST00000312635, ENST00000280377

IntEnz

3.4.19.12

HPA

ENSG00000135655-USP15

GeneCards

USP15

PRO

Q9Y4E8

Pharos - Targets

Q9Y4E8

GlyGen

Q9Y4E8

PDB

6CRN, 5JJW, 6GH9, 4A3O, 1W6V, 3PV1, 3PPA, 3T9L, 6GHA, 4A3P, 7R2G, 6CPM, 6DJ9, 6ML1, 3LMN

HMDB Protein

HMDBP10137

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q86TM6 SYVN1	1	SYVN1(1-617) [endoplasmic reticulum membrane] (R-HSA-535496)	0.668	8
UniProt:Q9H257 CARD9	3	CARD9 [cytosol] (R-HSA-561194) CARD9 [plasma membrane] (R-HSA-5607662) p-T231-CARD9 [plasma membrane] (R-HSA-5607623)	0.666	4
UniProt:Q9Y6D9 MAD1L1	1	MAD1L1 [cytosol] (R-HSA-141433)	0.556	3
UniProt:P19474 TRIM21	1	TRIM21 [cytosol] (R-HSA-976051)	0.556	3
UniProt:P60896 SEM1	2	SEM1 [cytosol] (R-HSA-8866674) SEM1 [nucleoplasm] (R-HSA-8866665)	0.527	2
UniProt:P53350 PLK1	4	PLK1 [cytosol] (R-HSA-164603) p-T210-PLK1 [nucleoplasm] (R-HSA-3002800) p-T210-PLK1 [cytosol] (R-HSA-3000318) PLK1 [nucleoplasm] (R-HSA-156720)	0.508	2

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