Degradation of ubiquitinated beta catenin by the proteasome

Stable Identifier
R-HSA-2130282
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
cytosol
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Degradation of ubiquitinated beta catenin by the proteasome
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Ubiquitinated beta-catenin is degraded by the proteasome.

Literature References
PubMed ID Title Journal Year
17183061 Docosahexaenoic Acid Induces Proteasome-dependent Degradation of {beta}-catenin, Down-regulation of Survivin and Apoptosis in Human Colorectal Cancer Cells not expressing COX-2

Calviello, G, Resci, F, Serini, S, Piccioni, E, Toesca, A, Boninsegna, A, Monego, G, Ranelletti, FO, Palozza, P

Carcinogenesis 2006
Participants
Input
Output
Participant Of
hasEvent
Event Information
Go Biological Process
proteasome-mediated ubiquitin-dependent protein catabolic process (0043161)
Catalyst Activity
Catalyst Activity
Title
endopeptidase activity of 26S proteasome [cytosol]
Physical Entity
26S proteasome [cytosol]
Activity
endopeptidase activity (0004175)
Orthologous Events
Degradation of ubiquitinated beta catenin by the proteasome (Caenorhabditis elegans)
Degradation of ubiquitinated beta catenin by the proteasome (Danio rerio)
Degradation of ubiquitinated beta catenin by the proteasome (Drosophila melanogaster)
Degradation of ubiquitinated beta catenin by the proteasome (Mus musculus)
Degradation of ubiquitinated beta catenin by the proteasome (Rattus norvegicus)
Degradation of ubiquitinated beta catenin by the proteasome (Sus scrofa)
Authored
Matthews, L  (2007-04-03)
Reviewed
Pagano, M  (2007-04-27)
Created
Rothfels, K  (2012-02-21)
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