ABL phosphorylates WAVEs

Stable Identifier
R-HSA-2130194
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Abelson interactor-1 (ABL) tyrosine kinase phosphorylates the strictly conserved tyrosine 150 in WAVE2 (Y151 in WAVE1 and WAVE3) (Leng et al. 2003, Chen et al. 2010).

Literature References
PubMed ID Title Journal Year
15657136 Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation

Leng, Y, Zhang, J, Badour, K, Arpaia, E, Freeman, S, Cheung, P, Siu, M, Siminovitch, K

Proc Natl Acad Sci U S A 2005
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein tyrosine kinase activity of ABL1 [cytosol]
Physical Entity
Activity
Orthologous Events
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