Reactome | HIST1H1D [nucleoplasm]

HIST1H1D [nucleoplasm]

Stable Identifier

R-HSA-211241

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

histone H1.3

Locations in the PathwayBrowser

Expand all

Cellular responses to stimuli (Homo sapiens)

- Cellular responses to stress (Homo sapiens)
  - Cellular Senescence (Homo sapiens)
    - DNA Damage/Telomere Stress Induced Senescence (Homo sapiens)
      - Formation of Senescence-Associated Heterochromatin Foci (SAHF) (Homo sapiens)
        
        SAHF formation (Homo sapiens)
        
        Histone H1 [nucleoplasm] (Homo sapiens)
        
        HIST1H1D [nucleoplasm] (Homo sapiens)
        
        Histone H1 bound chromatin DNA [nucleoplasm] (Homo sapiens)
        
        Histone H1 [nucleoplasm] (Homo sapiens)
        
        HIST1H1D [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:P16402 H1-3

Gene Names

H1-3, H1F3, HIST1H1D

Chain

initiator methionine:, chain:2-221

Reference Genes

BioGPS Gene:3007 H1-3

CTD Gene:3007 H1-3

dbSNP Gene:3007 H1-3

ENSEMBL:ENSG00000124575 HIST1H1D

ENSEMBL_homo_sapiens_GENE:ENSG00000124575.7 H1-3

HGNC:4717 H1-3

KEGG Gene (Homo sapiens):3007 H1-3

Monarch:3007 H1-3

NCBI Gene:3007 H1-3

OMIM:142210 H1-3

UCSC:P16402 H1-3

Reference Transcript

RefSeq:NM_005320.2 H1-3

Other Identifiers

11736915_at

17016393

214537_PM_at

214537_at

2946354

2946355

2946356

3007

33030_at

8124430

ADDON002924.hg

A_24_P260639

GE58004

GO:0000122

GO:0000785

GO:0000786

GO:0000791

GO:0003677

GO:0003690

GO:0003723

GO:0005198

GO:0005634

GO:0005694

GO:0006310

GO:0006325

GO:0006334

GO:0006351

GO:0006355

GO:0006357

GO:0030261

GO:0030527

GO:0031490

GO:0031492

GO:0043226

GO:0045910

GO:0065003

HMNXSV003044700

Hs.136857.0.S1_3p_at

ILMN_1749789

PH_hs_0008254

TC06001351.hg

Participates

as a candidate of

Histone H1 [nucleoplasm] (Homo sapiens)

Inferred To

Homologues of HIST1H1D [nucleoplasm] (Danio rerio)

H1f2 [nucleoplasm] (Rattus norvegicus)

HHO1 [nucleoplasm] (Saccharomyces cerevisiae)

H1 [nucleoplasm] (Dictyostelium discoideum)

HIST1H1D [nucleoplasm] (Danio rerio)

si:dkey-261m9.14 [nucleoplasm] (Danio rerio)

H1-2 [nucleoplasm] (Mus musculus)

zgc:110380 [nucleoplasm] (Danio rerio)

Cross References

RefSeq

NP_005311.1

OpenTargets

ENSG00000124575

HPA

ENSG00000124575-H1-3

GeneCards

P16402

Ensembl

ENSP00000244534, ENST00000244534, ENSG00000124575

PRO

P16402

Pharos - Targets

P16402

PDB

7XX5

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTC9 N	13	SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane] (R-COV-9729325) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus] (R-COV-9729339) N [plasma membrane] (R-COV-9694356) SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol] (R-COV-9756489) N [cytosol] (R-COV-9694300) p-S188,206-N [cytosol] (R-COV-9729324) p-8S-N [cytosol] (R-COV-9729335) p-8S,2T-N [cytosol] (R-COV-9729277) p-11S,2T-N [cytosol] (R-COV-9729264) p-11S,2T-metR95,177-N [cytosol] (R-COV-9729308) ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729275) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9729341) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729340)	0.527	2