Reactome | SPN [plasma membrane]

SPN [plasma membrane]

Stable Identifier

R-HSA-204438

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Leukosialin precursor, LEUK_HUMAN, CD43

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P16150 SPN

Gene Names

SPN, CD43

Chain

signal peptide:1-19, chain:20-400, chain:277-400

Reference Genes

BioGPS Gene:6693 SPN

COSMIC (genes):SPN SPN

CTD Gene:6693 SPN

dbSNP Gene:6693 SPN

ENSEMBL:ENSG00000197471 SPN

HGNC:11249 SPN

KEGG:hsa:6693 SPN

Monarch:6693 SPN

NCBI Gene:6693 SPN

OMIM:182160 SPN

UCSC:P16150 SPN

Reference Transcript

Other Identifiers

11735026_at

11735027_x_at

11747343_x_at

1568964_3p_x_at

1568964_PM_x_at

1568964_x_at

16817624

206056_PM_x_at

206056_x_at

206057_PM_x_at

206057_x_at

216981_3p_x_at

216981_PM_x_at

216981_x_at

3655575

3655576

3655577

3655578

3655579

3655580

3655581

3655582

3655583

3655584

3655586

3655588

3655589

3655590

3655591

3655592

3655607

3655609

3655611

3655613

3655615

36796_at

36798_g_at

6693

7994603

A_23_P433758

A_23_P433760

A_24_P407645

A_33_P3404706

GE59768

GE81238

GO:0001562

GO:0001808

GO:0001931

GO:0002296

GO:0002376

GO:0004888

GO:0005515

GO:0005604

GO:0005615

GO:0005634

GO:0005886

GO:0005902

GO:0006935

GO:0006955

GO:0006968

GO:0007155

GO:0007162

GO:0007163

GO:0007165

GO:0007166

GO:0009897

GO:0009986

GO:0016020

GO:0016605

GO:0030312

GO:0030544

GO:0031012

GO:0031072

GO:0031295

GO:0032609

GO:0032760

GO:0042098

GO:0042102

GO:0042130

GO:0042742

GO:0042995

GO:0043226

GO:0045060

GO:0050688

GO:0050776

GO:0050863

GO:0050868

GO:0050901

GO:0060089

GO:0070062

GO:0097190

GO:0098542

GO:2000404

GO:2000406

HMNXSV003032841

Hs.80738.0.A2_3p_at

Hs.80738.2.A1_3p_a_at

Hs2.343365.1.S1_3p_x_at

ILMN_1658017

ILMN_1660315

ILMN_1801040

M61827_rna1_s_at

PH_hs_0026412

TC16002068.hg

X52075_rna1_at

g4507180_3p_a_at

Participates

as a component of

BSG:SPN [plasma membrane] (Homo sapiens)

as an input of

Basigin interacts with CD43 (Homo sapiens)

as a member of

SELE ligands [plasma membrane] (Homo sapiens)

Inferred To

Spn [plasma membrane] (Mus musculus)

Spn [plasma membrane] (Rattus norvegicus)

SPN [plasma membrane] (Bos taurus)

SPN [plasma membrane] (Canis familiaris)

SPN [plasma membrane] (Sus scrofa)

Cross References

ENSEMBL

ENST00000360121, ENSP00000378787, ENST00000652691, ENSP00000498852, ENST00000563039, ENSP00000353238, ENST00000395389, ENSP00000455266

OpenTargets

ENSG00000197471

HPA

ENSG00000197471-SPN

PRO

P16150

Pharos - Targets

P16150

GlyGen

P16150

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O43765 SGTA	1	SGTA [cytosol] (R-HSA-5423595)	0.556	5
UniProt:Q9BQA9 CYBC1			0.556	3
UniProt:Q9Y282 ERGI3			0.556	3
UniProt:CXCL16 A0A6I8PIU0			0.556	3
IntAct:EBI-23667908 CCSB ORF ID			0.556	3
UniProt:Q59EV6 Q59EV6			0.556	3
UniProt:Q9UHD9 UBQLN2	1	UBQLN2 [cytosol] (R-HSA-8866007)	0.556	3
UniProt:Q04941 PLP2			0.556	3
UniProt:Q3SXY8 ARL13B	8	PolyUb-Misfolded ARL13B [lysosomal lumen] (R-HSA-9660004) PolyUb-Misfolded ARL13B [cytosol] (R-HSA-9641129) Ub-Misfolded ARL13B [cytosol] (R-HSA-9641119) Misfolded ARL13B [cytosol] (R-HSA-9640110) Misfolded ARL13B [cilium] (R-HSA-9640116) ARL13B [cilium] (R-HSA-5618181) PolyUb-Misfolded ARL13B [late endosome lumen] (R-HSA-9659986) ARL13B [plasma membrane] (R-HSA-9716787)	0.556	3
UniProt:Q9NR50 EIF2B3	1	EIF2B3 [cytosol] (R-HSA-72525)	0.527	2
UniProt:Q8N1S5 S39AB			0.527	3