Reactome | PDP1 [mitochondrial matrix]

PDP1 [mitochondrial matrix]

Stable Identifier

R-HSA-204149

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

PDP1 catalytic subunit 1

Locations in the PathwayBrowser

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Metabolism (Homo sapiens)

- The citric acid (TCA) cycle and respiratory electron transport (Homo sapiens)
  - Pyruvate metabolism and Citric Acid (TCA) cycle (Homo sapiens)
    - Pyruvate metabolism (Homo sapiens)
      - Regulation of pyruvate dehydrogenase (PDH) complex (Homo sapiens)
        
        PDP dephosphorylates p-lipo-PDH (Homo sapiens)
        
        PDP [mitochondrial matrix] (Homo sapiens)
        
        PDP1 complex [mitochondrial matrix] (Homo sapiens)
        
        PDP1 [mitochondrial matrix] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9P0J1 PDP1

Gene Names

PDP1, PDP, PPM2C

Chain

transit peptide:1-71, chain:72-537

Reference Genes

BioGPS Gene:54704 PDP1

COSMIC (genes):PDP1 PDP1

CTD Gene:54704 PDP1

dbSNP Gene:54704 PDP1

ENSEMBL:ENSG00000164951.16 PDP1

HGNC:9279 PDP1

KEGG Gene (Homo sapiens):54704 PDP1

Monarch:54704 PDP1

NCBI Gene:54704 PDP1

OMIM:605993 PDP1

UCSC:Q9P0J1 PDP1

Reference Transcript

Other Identifiers

11722230_a_at

11722231_at

11747314_a_at

17070926

218273_PM_s_at

218273_s_at

222572_PM_at

222572_at

3107343

3107344

3107345

3107346

3107348

3107349

3107350

3107351

3107352

3107353

54704

60812_at

60828_at

78594_at

8147344

88290_at

A_14_P131735

A_23_P123336

A_33_P3369761

GE56942

GO:0004721

GO:0004722

GO:0004741

GO:0005515

GO:0005622

GO:0005737

GO:0005739

GO:0005759

GO:0006470

GO:0016787

GO:0032991

GO:0035970

GO:0036211

GO:0043169

GO:0043226

GO:0045253

GO:0046872

GO:0140096

GO:1904184

HMNXSV003004400

Hs.22265.0.S2_3p_at

ILMN_1720631

ILMN_2218780

TC08000571.hg

g8923959_3p_a_at

Participates

as a component of

PDP1 complex [mitochondrial matrix] (Homo sapiens)

Inferred To

Pdp [mitochondrial matrix] (Drosophila melanogaster)

pdp1 [mitochondrial matrix] (Xenopus tropicalis)

PDP1 [mitochondrial matrix] (Bos taurus)

PDP1 [mitochondrial matrix] (Canis familiaris)

PDP1 [mitochondrial matrix] (Danio rerio)

PDP1 [mitochondrial matrix] (Gallus gallus)

PDP1 [mitochondrial matrix] (Mus musculus)

PDP1 [mitochondrial matrix] (Rattus norvegicus)

PDP1 [mitochondrial matrix] (Sus scrofa)

pdp-1 [mitochondrial matrix] (Caenorhabditis elegans)

Cross References

RefSeq

XP_011515438.1, NP_001155253.1, NP_060914.2, NP_001155251.1, NP_001155252.1

OpenTargets

ENSG00000164951

GeneCards

Q9P0J1

HPA

ENSG00000164951-PDP1

Ensembl

ENST00000297598, ENST00000396200, ENSP00000430380, ENST00000520728, ENSP00000428317, ENSG00000164951, ENST00000517764, ENSP00000379503, ENSP00000297598

PRO

Q9P0J1

Pharos - Targets

Q9P0J1

Orphanet

17188

HMDB Protein

HMDBP08786

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