Reactome | PLA2G6 [cytosol]

PLA2G6 [cytosol]

Stable Identifier

R-HSA-201596

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

iPLA2

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O60733 PLA2G6

Gene Names

PLA2G6, PLPLA9

Chain

chain:1-806

Reference Genes

BioGPS Gene:8398 PLA2G6

COSMIC (genes):PLA2G6 PLA2G6

CTD Gene:8398 PLA2G6

dbSNP Gene:8398 PLA2G6

ENSEMBL:ENSG00000184381 PLA2G6

ENSEMBL_homo_sapiens_GENE:ENSG00000184381.20 PLA2G6

HGNC:9039 PLA2G6

KEGG Gene (Homo sapiens):8398 PLA2G6

Monarch:8398 PLA2G6

NCBI Gene:8398 PLA2G6

OMIM:603604 PLA2G6

UCSC:O60733 PLA2G6

Reference Transcript

Other Identifiers

11739203_a_at

11747636_a_at

11754682_a_at

16934929

204691_PM_x_at

204691_x_at

210647_PM_x_at

210647_x_at

215938_3p_s_at

215938_PM_s_at

215938_s_at

3960389

3960390

3960391

3960392

3960393

3960394

3960395

3960400

3960403

3960407

3960409

3960412

3960417

3960418

3960419

3960420

3960421

3960422

3960423

3960425

3960426

3960429

3960430

3960436

3960437

41645_at

8076025

8398

A_23_P6464

A_33_P3421821

GE54590

GO:0002376

GO:0003824

GO:0003847

GO:0004622

GO:0004623

GO:0005515

GO:0005516

GO:0005576

GO:0005615

GO:0005634

GO:0005654

GO:0005737

GO:0005739

GO:0005829

GO:0005856

GO:0005886

GO:0006629

GO:0006935

GO:0015630

GO:0016020

GO:0016192

GO:0016290

GO:0016607

GO:0016787

GO:0017171

GO:0019731

GO:0023052

GO:0031143

GO:0032049

GO:0034638

GO:0035774

GO:0035965

GO:0038096

GO:0042802

GO:0042995

GO:0043226

GO:0046338

GO:0046469

GO:0046473

GO:0047499

GO:0098542

GO:0102545

GO:0102991

GO:2000304

HMNXSV003009651

HMNXSV003035126

Hs.120360.2.S1_3p_a_at

ILMN_1697654

ILMN_1798955

PH_hs_0023690

g5305593_3p_s_at

Participates

as a member of

Other forms of this molecule

PLA2G6 [mitochondrial inner membrane]

Inferred To

iPLA2-VIA [cytosol] (Drosophila melanogaster)

pla2g6 [cytosol] (Xenopus tropicalis)

PLA2G6 [cytosol] (Bos taurus)

PLA2G6 [cytosol] (Caenorhabditis elegans)

PLA2G6 [cytosol] (Canis familiaris)

PLA2G6 [cytosol] (Gallus gallus)

PLA2G6 [cytosol] (Sus scrofa)

Pla2g6 [cytosol] (Mus musculus)

Pla2g6 [cytosol] (Rattus norvegicus)

Cross References

RefSeq

NP_001186491.1, XP_016884470.1, XP_005261823.1, NP_001004426.1, XP_006724395.1, XP_005261822.1, XP_016884477.1, XP_016884471.1, XP_005261821.1, NP_003551.2

Guide to Pharmacology - Targets

1431

OpenTargets

ENSG00000184381

ZINC - Substances

PLPL9_HUMAN

ZINC target

O60733

PRO

O60733

IntEnz

3.1.2.2

HPA

ENSG00000184381-PLA2G6

GeneCards

O60733

Ensembl

ENSP00000499665, ENSP00000499712, ENSP00000386100, ENSP00000499555, ENST00000663895, ENSG00000184381, ENST00000335539, ENSP00000335149, ENST00000402064, ENST00000667521, ENSP00000333142, ENST00000332509, ENST00000660610

Pharos - Targets

O60733

ZINC - Predictions - Purchasable

PLPL9_HUMAN

Orphanet

15105

HMDB Protein

HMDBP00068

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8TAP6 CEP76	1	CEP76 [cytosol] (R-HSA-380281)	0.556	3
UniProt:Q9BVN2 RUSC1			0.556	3
IntAct:EBI-16439879 CCSB ORF ID			0.556	3
UniProt:Q86XT4 TRIM50	1	TRIM50 [cytosol] (R-HSA-5688976)	0.556	3
UniProt:Q70EL1-9 USP54			0.556	3
UniProt:B2RXF5 ZBT42			0.556	3
UniProt:Q8N1F7 NUP93	2	NUP93 [nuclear envelope] (R-HSA-157749) NUP93 [cytosol] (R-HSA-9634167)	0.556	3
UniProt:Q14140 SRTD2			0.556	3
UniProt:O60733 PLA2G6	2	PLA2G6 [mitochondrial inner membrane] (R-HSA-1524076) PLA2G6 [cytosol] (R-HSA-201596)	0.556	3
UniProt:O95199 RCBT2			0.556	3
UniProt:Q9NZL9 MAT2B	3	MAT2B [mitochondrial outer membrane] (R-HSA-5696871) PolyUb-MAT2B [mitochondrial outer membrane] (R-HSA-6783129) MAT2B [cytosol] (R-HSA-351214)	0.556	3
UniProt:Q9NWT6 HIF1AN	1	HIF1AN [cytosol] (R-HSA-1234154)	0.527	2