p75NTR signals via NF-kB

Stable Identifier
R-HSA-193639
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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p75NTR signals via NF-kB
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The NF-kB pathway is an important pro-survival signalling pathway activated by mature NGF, but not BDNF or NT-3, through p75NTR. It is unclear whether TRKA activity also affects NF-kB activation.

Literature References
PubMed ID Title Journal Year
16997282 NF-kappaB functions in the nervous system: from development to disease

Memet, S

Biochem Pharmacol 2006
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Events
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as an event of
Event Information
Go Biological Process
negative regulation of apoptotic process (0043066)
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p75NTR signals via NF-kB (Gallus gallus)
p75NTR signals via NF-kB (Mus musculus)
p75NTR signals via NF-kB (Rattus norvegicus)
p75NTR signals via NF-kB (Sus scrofa)
p75NTR signals via NF-kB (Xenopus tropicalis)
Authored
Nasi, S  (2006-10-10)
Annibali, D  (2006-10-10)
Reviewed
Friedman, WJ  (2008-05-20)
Chao, MV  (2008-05-28)
Created
Jassal, B  (2007-02-23)
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