In this reaction, FGF receptor in the plasma membrane binds an associating extracellular ligand, a requisite step for subsequent activation. The resulting complex consists of dimerized receptor, two ligand molecules, and heparan sulfate.
Ornitz, DM, Umemori, H, Mohammadi, M, Olsen, SK, Ibrahimi, OA, Zhang, X
Yamazaki, Y, Fukumoto, S, Shimada, T, Iijima, K, Urakawa, I, Okawa, K, Fujita, T, Yameshita, T, Hasegawa, H
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