Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Active TrkA receptor:p-FRS2:CRKL:RAPGEF1 [endosome membrane]
Stable Identifier
R-HSA-190070
Type
Complex
Species
Homo sapiens
Compartment
endosome membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by NTRKs (Homo sapiens)
Signaling by NTRK1 (TRKA) (Homo sapiens)
Signalling to ERKs (Homo sapiens)
Prolonged ERK activation events (Homo sapiens)
Frs2-mediated activation (Homo sapiens)
(Frs2)C3G stimulates nucleotide exchange on Rap1 (Homo sapiens)
Active TrkA receptor:p-FRS2:CRKL:RAPGEF1 [endosome membrane] (Homo sapiens)
p-FRS2:CRKL binds C3G (Homo sapiens)
Active TrkA receptor:p-FRS2:CRKL:RAPGEF1 [endosome membrane] (Homo sapiens)
Participants
components
Active TrkA receptor:p-FRS2:CRKL complex [endosome membrane]
(Homo sapiens)
RAPGEF1 [cytosol]
(Homo sapiens)
Participates
as an output of
p-FRS2:CRKL binds C3G (Homo sapiens)
Inferred To
Active TrkA receptor:p-FRS2:CRKL:RAPGEF1 [endosome membrane]
(Bos taurus)
Active TrkA receptor:p-FRS2:CRKL:RAPGEF1 [endosome membrane]
(Canis familiaris)
Active TrkA receptor:p-FRS2:CRKL:RAPGEF1 [endosome membrane]
(Gallus gallus)
Active TrkA receptor:p-FRS2:CRKL:RAPGEF1 [endosome membrane]
(Mus musculus)
Active TrkA receptor:p-FRS2:CRKL:RAPGEF1 [endosome membrane]
(Rattus norvegicus)
Active TrkA receptor:p-FRS2:CRKL:RAPGEF1 [endosome membrane]
(Sus scrofa)
Active TrkA receptor:p-FRS2:CRKL:RAPGEF1 [endosome membrane]
(Xenopus tropicalis)
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text