p-FRS2:CRKL binds C3G

Stable Identifier
R-HSA-170978
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Rap guanine nucleotide exchange factor 1 (RAPGEF1, C3G) is a guanine nucleotide exchange factor for Rap1, which is recruited by Crk adaptor proteins (Knudsen et al. 1994; York, 1998).

Literature References
PubMed ID Title Journal Year
9560161 Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

York, RD, Yao, H, Dillon, T, Ellig, CL, Eckert, SP, McCleskey, EW, Stork, PJ

Nature 1998
7806500 Four proline-rich sequences of the guanine-nucleotide exchange factor C3G bind with unique specificity to the first Src homology 3 domain of Crk

Knudsen, BS, Feller, SM, Hanafusa, H

J Biol Chem 1994
Participants
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