maltose + H2O => 2 D-glucose (maltase-glucoamylase)

Stable Identifier
R-HSA-189102
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
Digestion of maltose by maltase-glucoamylase to yield glucose
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The alpha-1,4 linkages of extracellular maltose are hydrolyzed to yield glucose in a reaction catalyzed by maltase-glucoamylase (Nichols et al. 1998; Semenza et al. 2001). In the body, this enzyme is found as a dimer on the external face of enterocytes in microvilli of the small intestine (Hauri et al. 1985), and acts on maltose derived directly from the diet and from the hydrolysis of starch.

Literature References
PubMed ID Title Journal Year
12547908 The maltase-glucoamylase gene: common ancestry to sucrase-isomaltase with complementary starch digestion activities

Nichols, BL, Avery, S, Sen, P, Swallow, DM, Hahn, D, Sterchi, EE

Proc Natl Acad Sci U S A 2003
3897250 Expression and intracellular transport of microvillus membrane hydrolases in human intestinal epithelial cells

Hauri, HP, Sterchi, EE, Bienz, D, Fransen, JA, Marxer, A

J Cell Biol 1985
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
alpha-1,4-glucosidase activity of MGAM dimer [plasma membrane]
Physical Entity
Activity
Orthologous Events
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