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Digestion of dietary carbohydrate
Stable Identifier
R-HSA-189085
DOI
10.3180/REACT_9472.2
Type
Pathway
Species
Homo sapiens
Compartment
extracellular region
,
plasma membrane
ReviewStatus
5/5
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Digestion and absorption (Homo sapiens)
Digestion (Homo sapiens)
Digestion of dietary carbohydrate (Homo sapiens)
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Carbohydrate is a major component of the human diet, and includes starch (amylose and amylopectin) and disaccharides such as sucrose, lactose, maltose and, in small amounts, trehalose. The digestion of starch begins with the action of amylase enzymes secreted in the saliva and small intestine, which convert it to maltotriose, maltose, limit dextrins, and some glucose. Digestion of the limit dextrins and disaccharides, both dietary and starch-derived, to monosaccharides - glucose, galactose, and fructose - is accomplished by enzymes located on the luminal surfaces of enterocytes lining the microvilli of the small intestine (Van Beers et al. 1995).
Literature References
PubMed ID
Title
Journal
Year
7555019
Intestinal brush border glycohydrolases: structure, function, and development
Büller, HA
,
Dekker, J
,
Einerhand, AW
,
Grand, RJ
,
Van Beers, EH
Crit. Rev. Biochem. Mol. Biol.
1995
Participants
Events
Digestion of linear starch (amylose) by extracellular amylase
(Homo sapiens)
Digestion of branched starch (amylopectin) by extracellular amylase
(Homo sapiens)
Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose
(Homo sapiens)
maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase)
(Homo sapiens)
maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase)
(Homo sapiens)
maltose + H2O => 2 D-glucose (maltase-glucoamylase)
(Homo sapiens)
maltose + H2O => 2 D-glucose (sucrase-isomaltase)
(Homo sapiens)
isomaltose + H2O => 2 D-glucose (sucrase-isomaltase)
(Homo sapiens)
lactose + H2O => D-glucose + D-galactose
(Homo sapiens)
sucrose + H2O => glucose + fructose
(Homo sapiens)
trehalose + H2O => 2 D-glucose
(Homo sapiens)
CHIA hydrolyses chitin
(Homo sapiens)
CHIT1 hydrolyses CHIT to 3xADGP
(Homo sapiens)
Participates
as an event of
Digestion (Homo sapiens)
Event Information
Go Biological Process
polysaccharide digestion (0044245)
Orthologous Events
Digestion of dietary carbohydrate (Bos taurus)
Digestion of dietary carbohydrate (Caenorhabditis elegans)
Digestion of dietary carbohydrate (Canis familiaris)
Digestion of dietary carbohydrate (Danio rerio)
Digestion of dietary carbohydrate (Dictyostelium discoideum)
Digestion of dietary carbohydrate (Drosophila melanogaster)
Digestion of dietary carbohydrate (Gallus gallus)
Digestion of dietary carbohydrate (Mus musculus)
Digestion of dietary carbohydrate (Plasmodium falciparum)
Digestion of dietary carbohydrate (Rattus norvegicus)
Digestion of dietary carbohydrate (Saccharomyces cerevisiae)
Digestion of dietary carbohydrate (Schizosaccharomyces pombe)
Digestion of dietary carbohydrate (Sus scrofa)
Digestion of dietary carbohydrate (Xenopus tropicalis)
Authored
D'Eustachio, P (2006-11-03)
Reviewed
Nichols, BL (2007-01-16)
Created
D'Eustachio, P (2006-11-03)
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