GTPase-activating protein (GAP) has two SH2 domains which bind only to PDGF beta-receptors on Tyr771. GAP does not bind the alpha-receptor. GAP converts Ras-GTP to Ras-GDP, deactivating Ras.
Kazlauskas, A, Kashishian, A, Cooper, JA
Ostman, A, Heldin, CH, Rönnstrand, L
Kazlauskas, A, Valius, M, Kashishian, A, Cooper, JA
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