I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol

Stable Identifier
R-HSA-1855219
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Inositol-tetrakisphosphate 1-kinase (ITPK1) dephosphorylates inositol 1,3,4,5,6-pentakisphosphate (I(1,3,4,5,6)P5) to inositol 3,4,5,6-tetrakisphosphate (I(3,4,5,6)P4) (Ho et al. 2002).
Literature References
PubMed ID Title Journal Year
11909533 Regulation of Ins(3,4,5,6)P(4) signaling by a reversible kinase/phosphatase

Zhang, T, Kwon, YU, Potter, BV, Carew, MA, Chung, SK, Riley, AM, Vogel, G, Hua, L, Ho, MW, Yang, X, Shears, SB, Adelt, S

Curr Biol 2002
Participants
Participates
Catalyst Activity

inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity of ITPK1:Mg2+ [cytosol]

Orthologous Events
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