IP3 and IP4 transport between cytosol and nucleus

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R-HSA-1855196
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Pathway
Species
Homo sapiens
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Inositol trisphosphate (IP3) and tetrakisphosphate (IP4) molecules are exported from the cytosol to the nucleus (Dewaste et al. 2003, Nalaskowski et al. 2002). It is unknown whether this occurs by diffusion or is mediated by a transporter.

Literature References
PubMed ID Title Journal Year
12027805 The human homologue of yeast ArgRIII protein is an inositol phosphate multikinase with predominantly nuclear localization

Nalaskowski, MM, Deschermeier, C, Fanick, W, Mayr, GW

Biochem J 2002
12747803 The three isoenzymes of human inositol-1,4,5-trisphosphate 3-kinase show specific intracellular localization but comparable Ca2+ responses on transfection in COS-7 cells

Dewaste, V, Moreau, C, De Smedt, F, Bex, F, De Smedt, H, Wuytack, F, Missiaen, L, Erneux, C

Biochem J 2003
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