MYO18A-p-2Y-FGFR1 fusion

Stable Identifier
R-HSA-1839006
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
MYO18A(1-1691)-p-FGFR1(429-822) fusion, t(8;17) MYO18A-p-FGFR1 fusion
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
15800673 The t(8;17)(p11;q23) in the 8p11 myeloproliferative syndrome fuses MYO18A to FGFR1

Walz, C, Chase, A, Schoch, C, Weisser, A, Schlegel, F, Hochhaus, A, Fuchs, R, Schmitt-Gräff, A, Hehlmann, R, Cross, NC, Reiter, A

Leukemia 2005
External Reference Information
External Reference
UniProt:Q92614 MYO18A
Gene Names
MYO18A, CD245, KIAA0216, MYSPDZ
Chain
chain:1-2054
Reference Genes
BioGPS Gene:399687 MYO18A
COSMIC (genes):MYO18A MYO18A
CTD Gene:399687 MYO18A
dbSNP Gene:399687 MYO18A
ENSEMBL:ENSG00000196535 MYO18A
ENSEMBL:ENSG00000196535 MYO18A
HGNC:31104 MYO18A
KEGG Gene (Homo sapiens):hsa:399687 MYO18A
Monarch:399687 MYO18A
NCBI Gene:399687 MYO18A
OMIM:609517 MYO18A
OMIM:610067 MYO18A
UCSC:Q92614 MYO18A
Reference Transcript
Other Identifiers
0001240021
0005910242
11718304_s_at
11750109_a_at
11750110_s_at
11751268_a_at
11751997_a_at
16842909
19646
202039_at
21121
36940_at
3751318
3751320
3751322
3751324
3751325
3751326
3751327
3751340
3751344
3751345
3751347
3751348
3751349
3751351
3751353
3751355
3751356
3751358
3751359
3751362
3751363
3751365
3751367
3751368
3751369
3751370
3751372
3751373
3751374
3751376
3751380
3751381
3751382
3751383
3751384
3751385
3751386
3751389
3751390
3751391
3751392
3751393
3751394
3751395
3751396
3751397
3751398
3751399
3751400
3751422
3751423
3751424
3751425
3751426
399687
8013860
A0A024QZ63
A0A0D9SFK2
A0A1B0GWJ6
A_23_P78122
A_33_P3238157
AAH39612
AAV80770
AB177858
AB177860
AY703984
BAA13206
BAD66836
BAD66838
BC039612
CAI45931
CCDS45641
CCDS45642
CH471159
CR933614
D86970
D86970_at
EAW51177
EAW51179
ENSG00000196535
ENSP00000434228
ENSP00000435932
ENSP00000437073
ENST00000527372
ENST00000531253
ENST00000533112
EntrezGene:399687
g4759231_3p_at
GE506328
GE510720
GE57371
GE865875
GO:0000139
GO:0000166
GO:0002376
GO:0003674
GO:0003677
GO:0003723
GO:0003774
GO:0003777
GO:0003779
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005623
GO:0005737
GO:0005793
GO:0005794
GO:0005802
GO:0005856
GO:0006259
GO:0006810
GO:0007010
GO:0007018
GO:0007030
GO:0008017
GO:0008092
GO:0008094
GO:0008150
GO:0008219
GO:0009986
GO:0016020
GO:0016192
GO:0016459
GO:0016477
GO:0016887
GO:0031032
GO:0032991
GO:0034641
GO:0040011
GO:0042641
GO:0043030
GO:0043066
GO:0043167
GO:0043226
GO:0043531
GO:0048194
GO:0048870
GO:0050714
GO:0051015
GO:0061024
GO:0090161
GO:0090164
GO:1903028
HGNC:31104
HPA019646
HPA021121
IPR000048
IPR001478
IPR001609
IPR002928
IPR020587
IPR027417
IPR031244
IPR036034
IPR036064
MIM:610067
MYO18A
MYO18A-202
MYO18A-209
MYO18A-214
NM_001346767
NM_078471
NM_203318
NP_001333696
NP_510880
NP_976063
PF00063
PF00595
PF01576
PH_hs_0023964
PR00193
SM00015
SM00228
SM00242
TC17001315.hg
uc002hdt.2
uc002hdu.2
uc010csa.2
UPI0000074364
UPI0000167F32
UPI0000252194
Participant Of
hasComponent
Other forms of this molecule
MYO18A-FGFR1 fusion [cytosol]
Modified Residues
Name
Insertion of residues 429 to 822 at 1692 from UniProt:P11362 FGFR1
Coordinate
1692
Name
O4'-phospho-L-tyrosine at 766
Coordinate
766
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at unknown position
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Disease
Name Identifier Synonyms
precursor lymphoblastic lymphoma/leukemia 5600
subacute leukemia 3264
myelodysplastic myeloproliferative cancer 4972 Myeloproliferative/Myelodysplastic syndromes, unclassifiable myelodysplastic myeloproliferative disease, Unclassifiable Myeloproliferative/Myelodysplastic syndrome, Myelodysplastic/myeloproliferative disease (morphologic abnormality)
Cross References
RefSeq
GeneCards
PRO