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Go!
LPA [extracellular region]
Stable Identifier
R-HSA-176877
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
apolipoprotein(a), apo(a)
Locations in the PathwayBrowser
Expand all
Transport of small molecules (Homo sapiens)
Plasma lipoprotein assembly, remodeling, and clearance (Homo sapiens)
Plasma lipoprotein remodeling (Homo sapiens)
LDL remodeling (Homo sapiens)
apolipoprotein(a) + LDL => Lp(a) (Homo sapiens)
LPA [extracellular region] (Homo sapiens)
Lp(a) [extracellular region] (Homo sapiens)
LPA [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P08519 LPA
Gene Names
LPA
Chain
signal peptide:1-19, chain:20-2040
Reference Genes
BioGPS Gene:4018 LPA
COSMIC (genes):LPA LPA
CTD Gene:4018 LPA
dbSNP Gene:4018 LPA
ENSEMBL:ENSG00000198670 LPA
ENSEMBL_homo_sapiens_GENE:ENSG00000198670.12 LPA
HGNC:6667 LPA
KEGG Gene (Homo sapiens):4018 LPA
Monarch:4018 LPA
NCBI Gene:4018 LPA
OMIM:152200 LPA
UCSC:P08519 LPA
Reference Transcript
RefSeq:NM_005577.2 LPA
Other Identifiers
11740823_s_at
11746858_a_at
11746859_a_at
17025359
207584_PM_at
207584_at
209978_PM_s_at
209978_s_at
210909_PM_x_at
2492661
2498398
2563067
2934685
2934710
2934721
2934730
2982637
2982639
2982643
2982647
2982648
2982649
2982651
2982652
2982654
2982662
2982669
2982677
2982684
2982686
2982692
2982731
2982732
2982733
2982734
2982737
2982738
2982739
2982741
2982742
2982743
2982744
2982746
2982747
2982748
2982750
2982751
2982752
2982753
2982754
2982755
2982756
2982757
2982758
2982759
2982760
2982761
2982762
2982763
2982764
2982766
2982767
2982768
2982769
2982770
2982771
2982772
2982773
2982787
2982788
2982800
2982802
2982804
2982806
2982808
2982810
2982812
2982816
2982818
2982820
2982822
2982828
2982830
2982835
2982837
2982839
2982841
2982847
2982849
2982851
2982855
2982857
2982859
2982875
2982877
2982879
31721_at
4018
8130608
A_23_P95221
A_24_P41801
GE59680
GO:0001968
GO:0003013
GO:0003824
GO:0004175
GO:0004252
GO:0004866
GO:0005102
GO:0005515
GO:0005576
GO:0005615
GO:0005886
GO:0006508
GO:0006629
GO:0006869
GO:0008015
GO:0008201
GO:0008233
GO:0008236
GO:0016787
GO:0019897
GO:0034185
GO:0034358
GO:0098772
GO:0140096
HMNXSV003029579
ILMN_1731670
ILMN_2260643
ILMN_2346987
PH_hs_0028627
TC06002281.hg
X06290_at
g5031884_3p_at
Participates
as a component of
Lp(a) [extracellular region] (Homo sapiens)
as an input of
apolipoprotein(a) + LDL => Lp(a) (Homo sapiens)
Cross References
RefSeq
NP_005568.2
OpenTargets
ENSG00000198670
GeneCards
P08519
HPA
ENSG00000198670-LPA
Ensembl
ENSP00000321334
,
ENST00000316300
,
ENSG00000198670
PRO
P08519
Pharos - Targets
P08519
Orphanet
24680
PDB
4BV7
,
1I71
,
4BVW
,
3KIV
,
4BVV
,
2FEB
,
4BVC
,
1JFN
,
4KIV
,
4BVD
,
6RX7
,
4BV5
,
1KIV
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P02749 APOH
2
APOH [extracellular region]
(R-HSA-8848905)
APOH [platelet dense granule lumen]
(R-HSA-8848901)
0.593
4
UniProt:P02751 FN1
10
FN1(32-2386) [platelet alpha granule lumen]
(R-HSA-114620)
FN1(32-271) [extracellular region]
(R-HSA-3787935)
FN1(272-2386) [extracellular region]
(R-HSA-3788024)
FN1(32-?) [extracellular region]
(R-HSA-2533850)
FN1(?-2386) [extracellular region]
(R-HSA-2533841)
FN1(32-1201)-p-7Y-ALK(1022-1620) fusion [plasma membrane]
(R-HSA-9713462)
FN1(32-1201)-ALK(1022-1620) fusion [plasma membrane]
(R-HSA-9713459)
p-FN1 [endoplasmic reticulum lumen]
(R-HSA-8956937)
FN1 [endoplasmic reticulum lumen]
(R-HSA-8956708)
FN1(32-2386) [extracellular region]
(R-HSA-54851)
0.592
2
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