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LPA [extracellular region]
Stable Identifier
R-HSA-176877
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
apolipoprotein(a), apo(a)
Locations in the PathwayBrowser
Expand all
Transport of small molecules (Homo sapiens)
Plasma lipoprotein assembly, remodeling, and clearance (Homo sapiens)
Plasma lipoprotein remodeling (Homo sapiens)
LDL remodeling (Homo sapiens)
apolipoprotein(a) + LDL => Lp(a) (Homo sapiens)
LPA [extracellular region] (Homo sapiens)
Lp(a) [extracellular region] (Homo sapiens)
LPA [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P08519 LPA
Gene Names
LPA
Chain
signal peptide:1-19, chain:20-4548
Reference Genes
COSMIC (genes):LPA LPA
ENSEMBL:ENSG00000198670 LPA
HGNC:6667 LPA
OMIM:152200 LPA
UCSC:P08519 LPA
Other Identifiers
0006550095
11740823_s_at
11746858_a_at
11746859_a_at
17025359
207584_at
209978_s_at
2492661
2498398
2563067
2934685
2934710
2934721
2934730
2982637
2982639
2982643
2982647
2982648
2982649
2982651
2982652
2982654
2982662
2982669
2982677
2982684
2982686
2982692
2982731
2982732
2982733
2982734
2982737
2982738
2982739
2982741
2982742
2982743
2982744
2982746
2982747
2982748
2982750
2982751
2982752
2982753
2982754
2982755
2982756
2982757
2982758
2982759
2982760
2982761
2982762
2982763
2982764
2982766
2982767
2982768
2982769
2982770
2982771
2982772
2982773
2982775
2982777
2982779
2982781
2982783
2982786
2982787
2982788
2982800
2982802
2982804
2982806
2982808
2982810
2982812
2982816
2982818
2982820
2982822
2982828
2982830
2982833
2982835
2982837
2982839
2982841
2982847
2982849
2982851
2982855
2982857
2982859
2982875
2982877
2982879
31721_at
4018
8130608
A_23_P95221
A_24_P41801
GE59680
GO:0001968
GO:0003013
GO:0003674
GO:0004252
GO:0004866
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0006508
GO:0006629
GO:0006810
GO:0006869
GO:0008015
GO:0008150
GO:0008201
GO:0008233
GO:0008236
GO:0010951
GO:0016787
GO:0030234
GO:0032991
GO:0034185
GO:0034358
GO:0034374
GO:0043167
ILMN_1731670
ILMN_2260643
ILMN_2346987
ILMN_3301551
PH_hs_0028627
TC06002281.hg
X06290_at
g5031884_3p_at
Participant Of
hasComponent
Lp(a) [extracellular region]
input
apolipoprotein(a) + LDL => Lp(a)
Inferred To
plg [extracellular region] (Danio rerio)
LPA [extracellular region] (Xenopus tropicalis)
Plg [extracellular region] (Mus musculus)
Plg [extracellular region] (Rattus norvegicus)
Cross References
OpenTargets
ENSG00000198670
HPA
ENSG00000198670-LPA
GeneCards
P08519
Ensembl
ENSG00000198670
,
ENSP00000395608
,
ENST00000447678
,
ENSP00000321334
,
ENST00000316300
PRO
P08519
Orphanet
24680
PDB
1JFN
,
4KIV
,
4BVW
,
4BV5
,
4BVD
,
4BV7
,
1KIV
,
1I71
,
6RX7
,
3KIV
,
4BVC
,
4BVV
,
2FEB
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P02749 APOH
2
APOH [platelet dense granule lumen]
(R-HSA-8848901)
APOH [extracellular region]
(R-HSA-8848905)
0.593
4
UniProt:P02751 FN1
8
FN1(32-271) [extracellular region]
(R-HSA-3787935)
FN1(32-2386) [platelet alpha granule lumen]
(R-HSA-114620)
FN1(272-2386) [extracellular region]
(R-HSA-3788024)
FN1(32-?) [extracellular region]
(R-HSA-2533850)
FN1(?-2386) [extracellular region]
(R-HSA-2533841)
p-FN1 [endoplasmic reticulum lumen]
(R-HSA-8956937)
FN1 [endoplasmic reticulum lumen]
(R-HSA-8956708)
FN1(32-2386) [extracellular region]
(R-HSA-54851)
0.592
2
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