Suicidal integration leading to smaller circles of viral DNA

Stable Identifier
R-HSA-175250
Type
Reaction [dissociation]
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1
Compartment
Locations in the PathwayBrowser
General
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Following the integrase-mediated strand transfer reaction of autointegration, the integration complex must be disassembled and the gapped intermediate repaired, just as in normal integration.

Literature References
PubMed ID Title Journal Year
8883604 HIV cDNA integration: molecular biology and inhibitor development

Farnet, CM, Bushman, FD

AIDS 1996
  Retroviruses

Coffin, JM, Hughes, SH, Varmus, HE

  1997
  Genetic Engineering: Principles and Methods

Setlow, JK

  1998
Participants
Participant Of
Disease
Name Identifier Synonyms
Human immunodeficiency virus infectious disease 526 HIV infection
Authored
Reviewed
Created
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