ARMS-mediated activation

Stable Identifier
R-HSA-170984
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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ARMS-mediated activation
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ARMS (Ankyrin-Rich Membrane Spanning/Kidins 220) is a 220kD tetraspanning adaptor protein which becomes rapidly tyrosine phosphorylated by active Trk receptors. ARMS is another adaptor protein which is involved in the activation of Rap1 and the subsequent prolonged activation of the MAPK cascade.
Literature References
PubMed ID Title Journal Year
9069267 Signal transduction by the neurotrophin receptors

Miller, FD, Kaplan, DR

Curr Opin Cell Biol 1997
Participants
Events
Participates
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Event Information
Go Biological Process
MAPK cascade (0000165)
Orthologous Events
ARMS-mediated activation (Bos taurus)
ARMS-mediated activation (Canis familiaris)
ARMS-mediated activation (Danio rerio)
ARMS-mediated activation (Gallus gallus)
ARMS-mediated activation (Mus musculus)
ARMS-mediated activation (Rattus norvegicus)
ARMS-mediated activation (Sus scrofa)
ARMS-mediated activation (Xenopus tropicalis)
Authored
Nasi, S  (2006-10-10)
Annibali, D  (2006-10-10)
Reviewed
Greene, LA  (2007-11-08)
Created
Jassal, B  (2006-01-25)
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