Phosphorylation of DSIF by the P-TEFb(Cyclin T1:Cdk9) complex

Stable Identifier
R-HSA-170704
Type
Reaction
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1
Compartment
Locations in the PathwayBrowser
Summation

Phosphorylation of the Spt5 subunit of DSIF by P-TEFb(Cyclin T1:Cdk9) results in the conversion of DSIF to an elongation factor (Ivanov al. 2000).

Literature References
PubMed ID Title Journal Year
10757782 Domains in the SPT5 protein that modulate its transcriptional regulatory properties

Ivanov, D, Kwak, YT, Guo, J, Gaynor, RB

Mol Cell Biol 2000
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
kinase activity of Tat-containing early elongation complex with hyperphosphorylated Pol II CTD and phospho-NELF [nucleoplasm]
Physical Entity
Activity
Disease
Name Identifier Synonyms
Human immunodeficiency virus infectious disease 526 HIV infection
Authored
Created