Ligand binds to TLR7 or TLR8

Stable Identifier
Reaction [binding]
Homo sapiens
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Endosomal recognition of influenza genomic RNA and imidazoquinoline compounds occurs by means of TLR7 and TLR8.

Literature References
PubMed ID Title Journal Year
14976261 Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

Diebold, SS, Kaisho, T, Hemmi, H, Akira, S, Reis e Sousa, C

Science 2004
12032557 Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848

Jurk, M, Heil, F, Vollmer, J, Schetter, C, Krieg, AM, Wagner, H, Lipford, G, Bauer, S

Nat Immunol 2002
11812998 Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

Hemmi, H, Kaisho, T, Takeuchi, O, Sato, S, Sanjo, H, Hoshino, K, Horiuchi, T, Tomizawa, H, Takeda, K, Akira, S

Nat Immunol 2002
14976262 Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

Heil, F, Hemmi, H, Hochrein, H, Ampenberger, F, Kirschning, C, Akira, S, Lipford, G, Wagner, H, Bauer, S

Science 2004
Participant Of
Orthologous Events