Reactome | PROZ(24-400) [endoplasmic reticulum lumen]

PROZ(24-400) [endoplasmic reticulum lumen]

Stable Identifier

R-HSA-163816

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Synonyms

pro-protein Z, uncarboxylated

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P22891 PROZ

Gene Names

PROZ

Chain

signal peptide:1-23, propeptide:24-40, chain:41-400

Reference Genes

BioGPS Gene:8858 PROZ

COSMIC (genes):PROZ PROZ

CTD Gene:8858 PROZ

dbSNP Gene:8858 PROZ

ENSEMBL:ENSG00000126231 PROZ

ENSEMBL:ENSG00000126231.15 PROZ

HGNC:9460 PROZ

KEGG Gene (Homo sapiens):8858 PROZ

Monarch:8858 PROZ

NCBI Gene:8858 PROZ

OMIM:176895 PROZ

UCSC:P22891 PROZ

Reference Transcript

Other Identifiers

11738558_a_at

11744546_a_at

16776812

208034_PM_s_at

208034_s_at

3502477

3502478

3502479

3502480

3502482

3502483

3502485

3502488

3502490

3502491

3502492

3502493

3502494

37109_at

7970251

8858

A_23_P140074

GE53873

GO:0003824

GO:0004252

GO:0005509

GO:0005515

GO:0005576

GO:0005615

GO:0005783

GO:0005788

GO:0005794

GO:0005796

GO:0006508

GO:0007596

GO:0007599

GO:0016787

GO:0042060

GO:0043226

GO:0070062

GO:0140096

HMNXSV003040703

ILMN_1664565

M55671_at

PH_hs_0000128

TC13000418.hg

g4506120_3p_a_at

Participates

as an input of

GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) (Homo sapiens)

Other forms of this molecule

PROZ(24-40) [Golgi lumen]

13xCbxE-PROZ(24-400) [endoplasmic reticulum lumen]

13xCbxE-PROZ(24-400) [Golgi lumen]

13xCbxE-PROZ [Golgi lumen]

Inferred To

Proz [endoplasmic reticulum lumen] (Mus musculus)

Proz [endoplasmic reticulum lumen] (Rattus norvegicus)

fi12c10 [endoplasmic reticulum lumen] (Danio rerio)

proz [endoplasmic reticulum lumen] (Xenopus tropicalis)

wu:fj51g06 [endoplasmic reticulum lumen] (Danio rerio)

PROZ [endoplasmic reticulum lumen] (Bos taurus)

Homologues of PROZ(24-400) [endoplasmic reticulum lumen] (Danio rerio)

PROZ(24-400) [endoplasmic reticulum lumen] (Danio rerio)

PROZ(24-400) [endoplasmic reticulum lumen] (Gallus gallus)

Cross References

RefSeq

NP_001243063.1, NP_003882.1

OpenTargets

ENSG00000126231

GeneCards

P22891

HPA

ENSG00000126231-PROZ

Ensembl

ENSP00000364697, ENST00000375547, ENSP00000344458, ENSG00000126231, ENST00000342783

PRO

P22891

Pharos - Targets

P22891

Orphanet

22600

HMDB Protein

HMDBP02005

PDB

3F1S, 3H5C

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UK55 SERPINA10	2	p-SERPINA10 [endoplasmic reticulum lumen] (R-HSA-8956990) SERPINA10 [endoplasmic reticulum lumen] (R-HSA-8956739)	0.655	7