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13xCbxE-PROZ(24-400) [endoplasmic reticulum lumen]
Stable Identifier
R-HSA-163838
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
pro-protein Z
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Homo sapiens)
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins (Homo sapiens)
Gamma-carboxylation of protein precursors (Homo sapiens)
GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) (Homo sapiens)
13xCbxE-PROZ(24-400) [endoplasmic reticulum lumen] (Homo sapiens)
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus (Homo sapiens)
Gamma-carboxy pro-protein Z transport from the endoplasmic reticulum to the Golgi apparatus (Homo sapiens)
13xCbxE-PROZ(24-400) [endoplasmic reticulum lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P22891 PROZ
Gene Names
PROZ
Chain
signal peptide:1-23, propeptide:24-40, chain:41-400
Reference Genes
BioGPS Gene:8858 PROZ
COSMIC (genes):PROZ PROZ
CTD Gene:8858 PROZ
dbSNP Gene:8858 PROZ
ENSEMBL:ENSG00000126231 PROZ
HGNC:9460 PROZ
Monarch:8858 PROZ
NCBI Gene:8858 PROZ
OMIM:176895 PROZ
UCSC:P22891 PROZ
Reference Transcript
RefSeq:NM_001256134.1 PROZ
RefSeq:NM_003891.2 PROZ
Other Identifiers
11738558_a_at
11744546_a_at
16776812
208034_PM_s_at
208034_s_at
3502477
3502478
3502479
3502480
3502482
3502483
3502485
3502486
3502487
3502488
3502489
3502490
3502491
3502492
3502493
3502494
37109_at
7970251
8858
A_23_P140074
GE53873
GO:0003824
GO:0004252
GO:0005509
GO:0005515
GO:0005576
GO:0005615
GO:0005788
GO:0005796
GO:0006508
GO:0007596
GO:0016787
GO:0043226
GO:0070062
GO:0140096
HMNXSV003040703
ILMN_1664565
M55671_at
PH_hs_0000128
TC13000418.hg
g4506120_3p_a_at
Participates
as an input of
Gamma-carboxy pro-protein Z transport from the endoplasmic reticulum to the Golgi apparatus (Homo sapiens)
as an output of
GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) (Homo sapiens)
Other forms of this molecule
PROZ(24-40) [Golgi lumen]
13xCbxE-PROZ [Golgi lumen]
13xCbxE-PROZ(24-400) [Golgi lumen]
PROZ(24-400) [endoplasmic reticulum lumen]
Inferred To
13xCbxE-PROZ(24-400) [endoplasmic reticulum lumen]
(Bos taurus)
13xCbxE-PROZ(24-400) [endoplasmic reticulum lumen]
(Gallus gallus)
Proz [endoplasmic reticulum lumen]
(Mus musculus)
Proz [endoplasmic reticulum lumen]
(Rattus norvegicus)
proza [endoplasmic reticulum lumen]
(Danio rerio)
proz [endoplasmic reticulum lumen]
(Xenopus tropicalis)
Modified Residues
Name
L-gamma-carboxyglutamic acid at 47
Coordinate
47
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 48
Coordinate
48
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 51
Coordinate
51
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 55
Coordinate
55
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 57
Coordinate
57
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 60
Coordinate
60
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 61
Coordinate
61
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 66
Coordinate
66
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 67
Coordinate
67
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 70
Coordinate
70
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 73
Coordinate
73
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 75
Coordinate
75
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 80
Coordinate
80
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Cross References
ENSEMBL
ENST00000342783
,
ENSP00000344458
,
ENST00000375547
,
ENSP00000364697
OpenTargets
ENSG00000126231
HPA
ENSG00000126231-PROZ
PRO
P22891
Pharos - Targets
P22891
Orphanet
PROZ
HMDB Protein
HMDBP02005
PDB
3H5C
,
3F1S
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9UK55 SERPINA10
2
p-SERPINA10 [endoplasmic reticulum lumen]
(R-HSA-8956990)
SERPINA10 [endoplasmic reticulum lumen]
(R-HSA-8956739)
0.655
7
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