Reactome | GLA [lysosomal lumen]

GLA [lysosomal lumen]

Stable Identifier

R-HSA-1605763

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

lysosomal lumen

Synonyms

Alpha-galactosidase A, AGAL_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P06280 GLA

Gene Names

GLA

Chain

signal peptide:1-31, chain:32-429

Reference Genes

BioGPS Gene:2717 GLA

COSMIC (genes):GLA GLA

CTD Gene:2717 GLA

dbSNP Gene:2717 GLA

ENSEMBL:ENSG00000102393 GLA

HGNC:4296 GLA

KEGG Gene (Homo sapiens):2717 GLA

Monarch:2717 GLA

NCBI Gene:2717 GLA

OMIM:300644 GLA

Reference Transcript

RefSeq:NM_000169.2 GLA

Other Identifiers

0002760047

11716718_at

11716719_s_at

17112769

214430_at

2717

36833_at

4015764

4015765

4015766

4015769

4015770

4015772

4015777

4015779

4015780

4015781

4015782

8174076

A_23_P45475

GE62124

GO:0002376

GO:0003674

GO:0003824

GO:0004553

GO:0004557

GO:0005102

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005737

GO:0005764

GO:0005773

GO:0005794

GO:0005975

GO:0006629

GO:0006687

GO:0006810

GO:0008150

GO:0008152

GO:0009056

GO:0009058

GO:0009311

GO:0016139

GO:0016192

GO:0016787

GO:0016798

GO:0016936

GO:0017041

GO:0031410

GO:0034641

GO:0035578

GO:0042803

GO:0043202

GO:0043226

GO:0043312

GO:0045019

GO:0046477

GO:0046479

GO:0051001

GO:0052692

GO:0070062

Hs.69089.0.S1_3p_at

ILMN_1766637

PH_hs_0004093

X14448_at

Participant Of

hasComponent

GLA dimer [lysosomal lumen]

Other forms of this molecule

GLA [extracellular region]

GLA [azurophil granule lumen]

Inferred To

Dmel\CG5731 [lysosomal lumen] (Drosophila melanogaster)

melA [lysosomal lumen] (Dictyostelium discoideum)

gla [lysosomal lumen] (Danio rerio)

gla [lysosomal lumen] (Xenopus tropicalis)

Gla [lysosomal lumen] (Mus musculus)

Gla [lysosomal lumen] (Rattus norvegicus)

Homologues of GLA [lysosomal lumen] (Dictyostelium discoideum)

Homologues of GLA [lysosomal lumen] (Drosophila melanogaster)

Dmel\CG7997 [lysosomal lumen] (Drosophila melanogaster)

GLA [lysosomal lumen] (Bos taurus)

GLA [lysosomal lumen] (Canis familiaris)

GLA [lysosomal lumen] (Dictyostelium discoideum)

GLA [lysosomal lumen] (Gallus gallus)

GLA [lysosomal lumen] (Sus scrofa)

gana-1 [lysosomal lumen] (Caenorhabditis elegans)

mel1 [lysosomal lumen] (Schizosaccharomyces pombe)

Cross References

RefSeq

NP_000160.1

ZINC - World Drugs

AGAL_HUMAN

OpenTargets

ENSG00000102393

ZINC - Substances

AGAL_HUMAN

ZINC target

P06280

ZINC - Biogenic

AGAL_HUMAN

PRO

P06280

PDB

3GXT, 3HG3, 3TV8, 1R47, 6IBK, 3HG4, 3LXB, 1R46, 3GXN, 3LX9, 3LXC, 6IBT, 6IBM, 3HG5, 3S5Y, 3GXP, 3HG2, 6IBR, 3S5Z, 3LXA, 4NXS

ZINC - Metabolites

AGAL_HUMAN

IntEnz

3.2.1.22

HPA

ENSG00000102393-GLA

GeneCards

P06280

Ensembl

ENSG00000102393, ENST00000218516, ENSP00000218516

Orphanet

16135

ZINC - Predictions - Purchasable

AGAL_HUMAN

HMDB Protein

HMDBP00723