Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
GLA [lysosomal lumen]
Stable Identifier
R-HSA-1605763
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lysosomal lumen
Synonyms
Alpha-galactosidase A, AGAL_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Sphingolipid metabolism (Homo sapiens)
Glycosphingolipid metabolism (Homo sapiens)
Glycosphingolipid catabolism (Homo sapiens)
GLA hydrolyzes PSAP(195-273):Gal2Cer:PE (Homo sapiens)
GLA dimer [lysosomal lumen] (Homo sapiens)
GLA [lysosomal lumen] (Homo sapiens)
GLA hydrolyzes PSAP(195-273):Gb3Cer:PE (Homo sapiens)
GLA dimer [lysosomal lumen] (Homo sapiens)
GLA [lysosomal lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P06280 GLA
Gene Names
GLA
Chain
signal peptide:1-31, chain:32-429
Reference Genes
BioGPS Gene:2717 GLA
COSMIC (genes):GLA GLA
CTD Gene:2717 GLA
dbSNP Gene:2717 GLA
ENSEMBL:ENSG00000102393 GLA
ENSEMBL:ENSG00000102393.14 GLA
HGNC:4296 GLA
KEGG Gene (Homo sapiens):2717 GLA
Monarch:2717 GLA
NCBI Gene:2717 GLA
OMIM:300644 GLA
Reference Transcript
RefSeq:NM_000169.2 GLA
Other Identifiers
11716718_at
11716719_s_at
17112769
214430_PM_at
214430_at
2717
36833_at
4015764
4015765
4015766
4015769
4015770
4015772
4015777
4015779
4015780
4015781
4015782
8174076
A_23_P45475
GE62124
GO:0003824
GO:0004553
GO:0004557
GO:0005102
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005764
GO:0005773
GO:0005794
GO:0005975
GO:0006629
GO:0008152
GO:0009311
GO:0016139
GO:0016787
GO:0016798
GO:0016936
GO:0017041
GO:0031410
GO:0035578
GO:0042803
GO:0043202
GO:0043226
GO:0045019
GO:0046477
GO:0046479
GO:0051001
GO:0052692
GO:0070062
GO:1901135
HMNXSV003004646
Hs.69089.0.S1_3p_at
ILMN_1766637
PH_hs_0004093
X14448_at
Participates
as a component of
GLA dimer [lysosomal lumen] (Homo sapiens)
Other forms of this molecule
GLA [extracellular region]
GLA [azurophil granule lumen]
Inferred To
gla [lysosomal lumen]
(Xenopus tropicalis)
Gla [lysosomal lumen]
(Rattus norvegicus)
GLA [lysosomal lumen]
(Bos taurus)
GLA [lysosomal lumen]
(Canis familiaris)
GLA [lysosomal lumen]
(Dictyostelium discoideum)
GLA [lysosomal lumen]
(Gallus gallus)
GLA [lysosomal lumen]
(Mus musculus)
GLA [lysosomal lumen]
(Sus scrofa)
zgc:101584 [lysosomal lumen]
(Danio rerio)
Cross References
RefSeq
NP_000160.1
ZINC - World Drugs
AGAL_HUMAN
OpenTargets
ENSG00000102393
ZINC - Substances
AGAL_HUMAN
ZINC target
P06280
ZINC - Biogenic
AGAL_HUMAN
PRO
P06280
PDB
3GXP
,
3HG3
,
3HG2
,
4NXS
,
3S5Y
,
3GXN
,
3LXC
,
6IBT
,
3LXB
,
3LXA
,
6IBR
,
6IBM
,
1R47
,
3GXT
,
3HG5
,
6IBK
,
3LX9
,
1R46
,
3S5Z
,
3HG4
,
3TV8
ZINC - Metabolites
AGAL_HUMAN
IntEnz
3.2.1.22
GeneCards
P06280
HPA
ENSG00000102393-GLA
Ensembl
ENST00000218516
,
ENSG00000102393
,
ENSP00000218516
Pharos - Targets
P06280
ZINC - Predictions - Purchasable
AGAL_HUMAN
Orphanet
16135
HMDB Protein
HMDBP00723
© 2023
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text