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GLA [azurophil granule lumen]
Stable Identifier
R-HSA-6798777
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
azurophil granule lumen
Synonyms
Alpha-galactosidase A, AGAL_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of azurophil granule lumen proteins (Homo sapiens)
Azurophil granule lumen proteins [azurophil granule lumen] (Homo sapiens)
GLA [azurophil granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P06280 GLA
Gene Names
GLA
Chain
signal peptide:1-31, chain:32-429
Reference Genes
BioGPS Gene:2717 GLA
COSMIC (genes):GLA GLA
CTD Gene:2717 GLA
dbSNP Gene:2717 GLA
ENSEMBL:ENSG00000102393 GLA
HGNC:4296 GLA
KEGG:hsa:2717 GLA
Monarch:2717 GLA
NCBI Gene:2717 GLA
OMIM:300644 GLA
UCSC:P06280 GLA
Reference Transcript
RefSeq:NM_000169.2 GLA
Other Identifiers
11716718_at
11716719_s_at
11760430_at
17112769
214430_PM_at
214430_at
2717
36833_at
4015760
4015762
4015764
4015765
4015766
4015767
4015768
4015769
4015770
4015771
4015772
4015773
4015774
4015775
4015776
4015777
4015779
4015780
4015781
4015782
8174076
A_23_P45475
GE602052
GE62124
GO:0003824
GO:0004553
GO:0004557
GO:0005102
GO:0005515
GO:0005576
GO:0005737
GO:0005764
GO:0005773
GO:0005794
GO:0005975
GO:0006629
GO:0007155
GO:0009311
GO:0016139
GO:0016787
GO:0016798
GO:0016936
GO:0019915
GO:0030168
GO:0030431
GO:0031133
GO:0035578
GO:0042803
GO:0043202
GO:0043226
GO:0045019
GO:0046477
GO:0046479
GO:0051001
GO:0070062
GO:0070527
GO:0090325
GO:1901135
HMNXSV003004646
Hs.69089.0.S1_3p_at
ILMN_1766637
PH_hs_0004093
TC0X001219.hg
X14448_at
Participates
as a member of
Azurophil granule lumen proteins [azurophil granule lumen] (Homo sapiens)
Other forms of this molecule
GLA [extracellular region]
GLA [lysosomal lumen]
Inferred To
mel1 [azurophil granule lumen]
(Schizosaccharomyces pombe)
Gla [azurophil granule lumen]
(Rattus norvegicus)
Homologues of GLA [azurophil granule lumen]
(Dictyostelium discoideum)
gana-1 [azurophil granule lumen]
(Caenorhabditis elegans)
GLA [azurophil granule lumen]
(Bos taurus)
GLA [azurophil granule lumen]
(Canis familiaris)
GLA [azurophil granule lumen]
(Dictyostelium discoideum)
GLA [azurophil granule lumen]
(Gallus gallus)
GLA [azurophil granule lumen]
(Mus musculus)
GLA [azurophil granule lumen]
(Sus scrofa)
gla [azurophil granule lumen]
(Xenopus tropicalis)
Cross References
ZINC - World Drugs
AGAL_HUMAN
OpenTargets
ENSG00000102393
ENSEMBL
ENST00000218516
,
ENSP00000218516
ZINC - Substances
AGAL_HUMAN
ZINC - Biogenic
AGAL_HUMAN
ZINC target
P06280
PRO
P06280
GlyGen
P06280
PDB
6IBM
,
6IBK
,
3LX9
,
4NXS
,
3S5Y
,
3S5Z
,
3HG5
,
8K7G
,
8K7L
,
8K7D
,
3HG4
,
8K7F
,
9AVS
,
3HG2
,
3HG3
,
1R47
,
1R46
,
3GXP
,
3GXT
,
6IBT
,
3LXC
,
3GXN
,
8K7E
,
3TV8
,
6IBR
,
3LXB
,
3LXA
,
8K7J
,
8K7H
,
8K7K
,
8K7I
ZINC - Metabolites
AGAL_HUMAN
IntEnz
3.2.1.22
HPA
ENSG00000102393-GLA
Pharos - Targets
P06280
Orphanet
GLA
ZINC - Predictions - Purchasable
AGAL_HUMAN
HMDB Protein
HMDBP00723
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P27824 CANX
2
CANX [endoplasmic reticulum lumen]
(R-HSA-195906)
CANX [lumenal side of endoplasmic reticulum membrane]
(R-HSA-983091)
0.527
2
UniProt:Q2TAA5 ALG11
6
ALG11 Y279S [endoplasmic reticulum membrane]
(R-HSA-4570575)
ALG11 E398K [endoplasmic reticulum membrane]
(R-HSA-4570576)
ALG11 Q318P [endoplasmic reticulum membrane]
(R-HSA-4570582)
ALG11 L86S [endoplasmic reticulum membrane]
(R-HSA-4570580)
ALG11 L381S [endoplasmic reticulum membrane]
(R-HSA-4570581)
ALG11 [endoplasmic reticulum membrane]
(R-HSA-449267)
0.499
2
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