Ubiquitinated DVL is degraded by the proteasome

Stable Identifier
R-HSA-1504193
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
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Ubiquitinated Dishevelled is degraded by the proteasome.

Literature References
PubMed ID Title Journal Year
16547521 The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation

Angers, S, Thorpe, CJ, Biechele, TL, Goldenberg, SJ, Zheng, N, Maccoss, MJ, Moon, RT

Nat Cell Biol 2006
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
endopeptidase activity of 26S proteasome [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created