Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
PNPLA6 [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-1498821
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
Patatin-like phospholipase domain-containing protein 6, NTE, Neuropathy target esterase
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Phospholipid metabolism (Homo sapiens)
PI Metabolism (Homo sapiens)
Glycerophospholipid catabolism (Homo sapiens)
PNPLA6 hydrolyzes LysoPtdCho (Homo sapiens)
PNPLA6 [endoplasmic reticulum membrane] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
12514188
Protein domains, catalytic activity, and subcellular distribution of neuropathy target esterase in Mammalian cells
Li, Y
,
Dinsdale, D
,
Glynn, P
J. Biol. Chem.
2003
External Reference Information
External Reference
UniProt:Q8IY17 PNPLA6
Gene Names
PNPLA6, NTE
Chain
chain:1-1375
Reference Genes
BioGPS Gene:10908 PNPLA6
COSMIC (genes):PNPLA6 PNPLA6
CTD Gene:10908 PNPLA6
dbSNP Gene:10908 PNPLA6
ENSEMBL:ENSG00000032444 PNPLA6
ENSEMBL_homo_sapiens_GENE:ENSG00000032444.17 PNPLA6
HGNC:16268 PNPLA6
KEGG Gene (Homo sapiens):10908 PNPLA6
Monarch:10908 PNPLA6
NCBI Gene:10908 PNPLA6
OMIM:603197 PNPLA6
UCSC:Q8IY17 PNPLA6
Reference Transcript
RefSeq:NM_006702.4 PNPLA6
RefSeq:NM_001166113.1 PNPLA6
RefSeq:NM_001166111.1 PNPLA6
RefSeq:NM_001166114.1 PNPLA6
RefSeq:NM_001166112.1 PNPLA6
Other Identifiers
10908
11718554_a_at
11719565_x_at
11744537_a_at
11751934_a_at
11752867_a_at
16857630
203718_PM_at
203718_at
34874_at
3818890
3818891
3818892
3818893
3818894
3818896
3818898
3818899
3818900
3818901
3818902
3818903
3818904
3818906
3818907
3818909
3818910
3818911
3818912
3818914
3818915
3818916
3818917
3818919
3818920
3818921
3818922
3818923
3818925
3818928
3818930
3818931
3818935
3818936
3818938
3818939
3818940
3818942
3818943
3818944
3818945
3818947
3818951
3818956
3818959
3818960
3818961
3818962
3818963
3818964
63374_at
8025199
A_14_P112467
A_23_P16166
GE55157
GO:0003824
GO:0004622
GO:0005783
GO:0005789
GO:0005829
GO:0006629
GO:0016020
GO:0016042
GO:0016787
GO:0043226
GO:0046470
GO:0046475
GO:0102545
HMNXSV003054758
ILMN_1764383
ILMN_1799614
PH_hs_0028599
PH_hs_0041124
TC19000129.hg
g10092596_3p_s_at
g5729950_3p_at
Inferred To
Pnpla6 [endoplasmic reticulum membrane]
(Rattus norvegicus)
Homologues of PNPLA6 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
PNPLA6 [endoplasmic reticulum membrane]
(Bos taurus)
PNPLA6 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
PNPLA6 [endoplasmic reticulum membrane]
(Canis familiaris)
PNPLA6 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
PNPLA6 [endoplasmic reticulum membrane]
(Gallus gallus)
PNPLA6 [endoplasmic reticulum membrane]
(Mus musculus)
PNPLA6 [endoplasmic reticulum membrane]
(Saccharomyces cerevisiae)
PNPLA6 [endoplasmic reticulum membrane]
(Schizosaccharomyces pombe)
PNPLA6 [endoplasmic reticulum membrane]
(Sus scrofa)
Cross References
RefSeq
NP_001159584.1
,
NP_001159586.1
,
NP_001159585.1
,
NP_006693.3
,
NP_001159583.1
OpenTargets
ENSG00000032444
IntEnz
3.1.1.5
GeneCards
Q8IY17
HPA
ENSG00000032444-PNPLA6
Ensembl
ENSG00000032444
,
ENSP00000407509
,
ENST00000450331
,
ENSP00000394348
,
ENSP00000221249
,
ENST00000414982
,
ENST00000221249
,
ENST00000545201
,
ENSP00000443323
PRO
Q8IY17
Pharos - Targets
Q8IY17
Orphanet
17190
HMDB Protein
HMDBP10677
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text