Synthesis of PIPs at the ER membrane

Stable Identifier
R-HSA-1483248
DOI
10.3180/R-HSA-1483248.5
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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Synthesis of PIPs at the ER membrane
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At the endoplasmic reticulum (ER) membrane, phosphatidylinositol (PI) and phosphatidylinositol 4-phosphate (PI4P) are interconverted (Wong et al. 1997, Gehrmann et al. 1999, Wei et al. 2002, Rohde et al. 2003).
Literature References
PubMed ID Title Journal Year
12324459 Type II phosphatidylinositol 4-kinase beta is a cytosolic and peripheral membrane protein that is recruited to the plasma membrane and activated by Rac-GTP

Wei, YJ, Sun, HQ, Yamamoto, M, Wlodarski, P, Kunii, K, Martínez, M, Barylko, B, Albanesi, JP, Yin, HL

J Biol Chem 2002
9148941 Subcellular locations of phosphatidylinositol 4-kinase isoforms

Wong, K, Meyers, ddR, Cantley, LC

J Biol Chem 1997
10101268 Functional expression and characterisation of a new human phosphatidylinositol 4-kinase PI4K230

Gehrmann, T, Gülkan, H, Suer, S, Herberg, FW, Balla, A, Vereb, G, Mayr, GW, Heilmeyer LM, Jr

Biochim Biophys Acta 1999
14527956 The human phosphatidylinositol phosphatase SAC1 interacts with the coatomer I complex

Rohde, HM, Cheong, FY, Konrad, G, Paiha, K, Mayinger, P, Boehmelt, G

J Biol Chem 2003
Participants
Events
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as an event of
Event Information
Go Biological Process
phosphatidylinositol biosynthetic process (0006661)
Orthologous Events
Synthesis of PIPs at the ER membrane (Bos taurus)
Synthesis of PIPs at the ER membrane (Caenorhabditis elegans)
Synthesis of PIPs at the ER membrane (Canis familiaris)
Synthesis of PIPs at the ER membrane (Danio rerio)
Synthesis of PIPs at the ER membrane (Dictyostelium discoideum)
Synthesis of PIPs at the ER membrane (Drosophila melanogaster)
Synthesis of PIPs at the ER membrane (Gallus gallus)
Synthesis of PIPs at the ER membrane (Mus musculus)
Synthesis of PIPs at the ER membrane (Plasmodium falciparum)
Synthesis of PIPs at the ER membrane (Rattus norvegicus)
Synthesis of PIPs at the ER membrane (Saccharomyces cerevisiae)
Synthesis of PIPs at the ER membrane (Schizosaccharomyces pombe)
Synthesis of PIPs at the ER membrane (Sus scrofa)
Synthesis of PIPs at the ER membrane (Xenopus tropicalis)
Authored
Williams, MG  (2011-10-18)
Reviewed
Wakelam, M  (2012-05-14)
Created
Williams, MG  (2011-08-12)
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